Patterns of care and outcome of CIC‐rearranged sarcoma patients: A nationwide study of the French sarcoma group
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5539
Abstract: CIC‐rearranged sarcomas (CIC‐RS) represent the most frequent subset of “Ewing‐like” undifferentiated small round cell sarcomas. These tumors tend to be more aggressive than Ewing sarcomas. Moreover, treatment strategy can differ according to teams. The primary… read more here.
Keywords: cic; sarcoma; care outcome; cic rearranged ... See more keywords
Novel CIC variants identified in individuals with neurodevelopmental phenotypes
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24346
Abstract: Heterozygous pathogenic variants in CIC, which encodes a transcriptional repressor, have been identified in individuals with neurodevelopmental phenotypes. To date, 11 CIC variants have been associated with the CIC‐related neurodevelopmental syndrome. Here, we describe three… read more here.
Keywords: cic; partial loss; cic variants; individuals neurodevelopmental ... See more keywords
Determination of organically bound fluorine sum parameters in river water samples—comparison of combustion ion chromatography (CIC) and high resolution-continuum source-graphite furnace molecular absorption spectrometry (HR-CS-GFMAS)
Sign Up to like & getrecommendations! Published in 2020 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-03010-y
Abstract: In this study, we compare combustion ion chromatography (CIC) and high resolution-continuum source-graphite furnace molecular absorption spectrometry (HR-CS-GFMAS) with respect to their applicability for determining organically bound fluorine sum parameters. Extractable (EOF) and adsorbable (AOF)… read more here.
Keywords: cic; sum parameters; fluorine sum; bound fluorine ... See more keywords
Exosomes, metastases, and the miracle of cancer stem cell markers
Sign Up to like & getrecommendations! Published in 2019 at "Cancer and Metastasis Reviews"
DOI: 10.1007/s10555-019-09793-6
Abstract: Cancer-initiating cells (CIC) are the driving force in tumor progression. There is strong evidence that CIC fulfill this task via exosomes (TEX), which modulate and reprogram stroma, nontransformed cells, and non-CIC. Characterization of CIC, besides… read more here.
Keywords: tumor progression; exosomes metastases; cic; metastasis ... See more keywords
Evolution of male patients with detrusor underactivity and conservative treatment. Five-year follow-up.
Sign Up to like & getrecommendations! Published in 2020 at "Actas urologicas espanolas"
DOI: 10.1016/j.acuro.2020.08.004
Abstract: INTRODUCTION The objective of the study was to compare the evolution of male patients with neurogenic detrusor underactivity (NDU) versus non-neurogenic DU (NNDU) and to establish risk factors to predict the need for clean intermittent… read more here.
Keywords: evolution male; cic; treatment; male patients ... See more keywords
Durées de traitement et post-traitement des traitements systémiques dans une cohorte nationale française d’enfants ayant une dermatite atopique
Sign Up to like & getrecommendations! Published in 2020 at "Annales De Dermatologie Et De Venereologie"
DOI: 10.1016/j.annder.2020.09.048
Abstract: Introduction Les immunosuppresseurs (IS) sont limites aux formes severes de dermatite atopique (DA) pediatrique. Notre objectif etait de decrire leur utilisation (1re ligne [IS1] et 2e ligne [IS2]) entre 2008 et 2018 dans une cohorte retrospective pediatrique de DA multicentrique… read more here.
Keywords: enfants ayant; cic; mediane; traitement ... See more keywords
Coagulation and anticoagulation in COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "Blood Reviews"
DOI: 10.1016/j.blre.2020.100761
Abstract: COVID-19 has become a pandemic in the United States and worldwide. COVID-19-induced coagulopathy (CIC) is commonly encountered at presentation manifested by considerable elevation of D-dimer and fibrin split products but with modest or no change… read more here.
Keywords: anticoagulation; cic; covid; anticoagulation covid ... See more keywords
NUTM2A-CIC fusion small round cell sarcoma: a genetically distinct variant of CIC-rearranged sarcoma.
Sign Up to like & getrecommendations! Published in 2017 at "Human pathology"
DOI: 10.1016/j.humpath.2017.01.012
Abstract: CIC-rearranged sarcoma is a new entity of undifferentiated small round cell sarcoma characterized by chimeric fusions with CIC rearrangement. We report a NUTM2A-CIC fusion sarcoma in a 43-year-old woman who died of rapidly progressive disease.… read more here.
Keywords: sarcoma; cic fusion; cic; nutm2a cic ... See more keywords
Bladder management in children with transverse myelitis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pediatric urology"
DOI: 10.1016/j.jpurol.2021.04.003
Abstract: BACKGROUND Patients with transverse myelitis (TM) often present with urinary retention. While many recover their bladder function, some have persistent voiding dysfunction, and both intermediate and long-term outcomes are variable. OBJECTIVE In patients who develop… read more here.
Keywords: presentation; transverse myelitis; cic; bladder ... See more keywords
Quantitative determination of protamine using a fluorescent protein chromophore-based AIE probe
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron"
DOI: 10.1016/j.tet.2021.132218
Abstract: Abstract An aggregation induced emission (AIE) fluorescent protein chromophore derivative CIC-FP for detecting protamine and heparin under physiological environment was designed and synthesized. CIC-FP exhibited good biocompatibility and a large stoke shift (91 nm), thus well… read more here.
Keywords: cic; protein chromophore; protamine; quantitative determination ... See more keywords
CIC protein instability contributes to tumorigenesis in glioblastoma
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-018-08087-9
Abstract: Capicua (CIC) is a transcriptional repressor that counteracts activation of genes downstream of receptor tyrosine kinase (RTK)/Ras/ERK signaling. It is well-established that tumorigenesis, especially in glioblastoma (GBM), is attributed to hyperactive RTK/Ras/ERK signaling. While CIC… read more here.
Keywords: degradation; tumorigenesis; glioblastoma; cic protein ... See more keywords