Abstract 3721: The C1 domain of capicua has functional importance in human CIC-DUX4
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DOI: 10.1158/1538-7445.am2023-3721
Abstract: Genomic rearrangements between the HMG-box family transcriptional repressor capicua (CIC) and multiple partner genes result in fusion oncoproteins that activate transcription to drive sarcoma growth and progression. In the case of CIC-DUX4, the most common… read more here.
Keywords: cic; functional importance; cic dux4; human cic ... See more keywords