Systemic treatments and outcomes in CIC ‐rearranged Sarcoma: A national multi‐centre clinicopathological series and literature review
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DOI: 10.1002/cam4.4580
Abstract: CIC‐rearranged sarcoma is a recently established, ultra‐rare, molecularly defined sarcoma subtype. We aimed to further characterise clinical features of CIC‐rearranged sarcomas and explore clinical management including systemic treatments and outcomes. read more here.
Keywords: outcomes cic; systemic treatments; treatments outcomes; rearranged sarcoma ... See more keywords
Patterns of care and outcome of CIC‐rearranged sarcoma patients: A nationwide study of the French sarcoma group
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DOI: 10.1002/cam4.5539
Abstract: CIC‐rearranged sarcomas (CIC‐RS) represent the most frequent subset of “Ewing‐like” undifferentiated small round cell sarcomas. These tumors tend to be more aggressive than Ewing sarcomas. Moreover, treatment strategy can differ according to teams. The primary… read more here.
Keywords: cic; sarcoma; care outcome; cic rearranged ... See more keywords
NUTM2A-CIC fusion small round cell sarcoma: a genetically distinct variant of CIC-rearranged sarcoma.
Sign Up to like & getrecommendations! Published in 2017 at "Human pathology"
DOI: 10.1016/j.humpath.2017.01.012
Abstract: CIC-rearranged sarcoma is a new entity of undifferentiated small round cell sarcoma characterized by chimeric fusions with CIC rearrangement. We report a NUTM2A-CIC fusion sarcoma in a 43-year-old woman who died of rapidly progressive disease.… read more here.
Keywords: sarcoma; cic fusion; cic; nutm2a cic ... See more keywords
“Cyst” on the forearm of a 28‐year‐old female: Case report of a CIC‐rearranged sarcoma
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DOI: 10.1111/cup.13478
Abstract: Capicua transcriptional repressor (CIC)‐rearranged sarcomas are part of the group of Ewing‐like sarcomas or atypical Ewing sarcomas which, thanks to the progress in molecular diagnosis, are being defined by particular genetic abnormalities separating this group… read more here.
Keywords: old female; cyst; case; year old ... See more keywords
A case of CIC‐rearranged undifferentiated round‐cell sarcoma with exclusive spindled morphology and diffuse CD99 positivity: a potential pitfall
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DOI: 10.1111/his.13051
Abstract: CIC-rearranged sarcomas comprise a recognized subset of the so called “undifferentiated small round cell sarcomas” that lack the traditional EWSR1 fusion to one of the ETS family members.1 A smaller percentage have demonstrated BCOR gene… read more here.
Keywords: gene; round cell; cic rearranged;
Pancreaticoduodenectomy for a primary duodenal capicua transcriptional repressor (CIC) -rearranged sarcoma with severe bleeding: a case report
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DOI: 10.1186/s12876-020-01266-3
Abstract: Background Capicua transcriptional repressor (CIC) -rearranged sarcoma is characterized by small round cells, histologically similar to Ewing sarcoma. However, CIC-rearranged sarcoma has different clinical, histological, and immunohistochemical features from Ewing sarcoma. It is important to… read more here.
Keywords: rearranged sarcoma; capicua transcriptional; cic rearranged; tumor ... See more keywords
A global collaboRAtive study of CIC-rearranged, BCOR::CCNB3-rearranged and other ultra-rare unclassified undifferentiated small round cell sarcomas (GRACefUl).
Sign Up to like & getrecommendations! Published in 2023 at "European journal of cancer"
DOI: 10.2139/ssrn.4197931
Abstract: BACKGROUND Undifferentiated small round cell sarcomas (URCSs) represent a diagnostic challenge, and their optimal treatment is unknown. We aimed to define the clinical characteristics, treatment, and outcome of URCS patients. METHODS URCS patients treated from… read more here.
Keywords: ccnb3; ccnb3 rearranged; round cell; cic rearranged ... See more keywords