Endothelial-Specific Expression of CIDEC Protects From Age-Induced Skeletal Muscle Capillary Rarefaction and Declined Muscle Performance
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5795436
Abstract: We recently found that Cell death-inducing DNA fragmentation factor-a–like effector C (CIDEC), originally identified as lipid droplet-associated protein in adipocytes, is abundantly expressed in endothelial cells. We described its novel role in regulating vascular function… read more here.
Keywords: muscle performance; cidec; muscle; physiology ... See more keywords
CIDEC: A Potential Factor in Diabetic Vascular Inflammation
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DOI: 10.1159/000520685
Abstract: Cell death-inducing DFF45-like effector C (CIDEC) is involved in diet-induced adipose inflammation. Whether CIDEC plays a role in diabetic vascular inflammation remains unclear. A type 2 diabetic rat model was induced by high-fat diet and… read more here.
Keywords: inflammation; diabetic vascular; vascular inflammation; cidec ... See more keywords
Rare CIDEC coding variants enriched in age-related macular degeneration patients with small low-luminance deficit cause lipid droplet and fat storage defects
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DOI: 10.1371/journal.pone.0280484
Abstract: Background The basis of Age-related macular degeneration (AMD) genetic risk has been well documented; however, few studies have looked at genetic biomarkers of disease progression or treatment response within advanced AMD patients. Here we report… read more here.
Keywords: low luminance; coding variants; cidec; lipid droplet ... See more keywords
Endothelial-Specific Expression of CIDEC Improves High-Fat Diet-Induced Vascular and Metabolic Dysfunction.
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DOI: 10.2337/db22-0294
Abstract: Cell death-inducing DNA fragmentation factor-α-like effector C (CIDEC), originally identified to be a lipid-droplet associated protein in adipocytes, positively associates with insulin sensitivity. Recently, we discovered that it is expressed abundantly in human endothelial cells… read more here.
Keywords: cidec; expression cidec; endothelial specific; dysfunction ... See more keywords
Small Intestine-specific Knockout of CIDEC Improves Obesity and Hepatic Steatosis by Inhibiting Synthesis of Phosphatidic Acid
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DOI: 10.7150/ijbs.74348
Abstract: The small intestine is main site of exogenous lipid digestion and absorption, and it is important for lipid metabolic homeostasis. Cell death-inducing DNA fragmentation-factor like effector C (CIDEC) is active in lipid metabolism in tissues… read more here.
Keywords: intestine specific; small intestine; cidec; knockout ... See more keywords