Identification of ovalbumin-derived peptides as multi-target inhibitors of AChE, BChE and BACE1.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.10295
Abstract: BACKGROUND Alzheimer's disease (AD) is a kind of progressive neurodegenerative disease that occurs to the elderly. But there is no ideal treatment for AD. Thus, the purpose of this study is to identify anti-AD peptides… read more here.
Keywords: ache bche; bche bace1; bace1; cik ... See more keywords
Efficacy of adjuvant cytokine-induced killer cell immunotherapy in patients with colorectal cancer after radical resection
Sign Up to like & getrecommendations! Published in 2020 at "Oncoimmunology"
DOI: 10.1080/2162402x.2020.1752563
Abstract: ABSTRACT Adjuvant chemotherapy after surgery is the standard treatment modality for stage III and part of stage II or stage IV colorectal cancer (CRC) patients. However, the 5-year overall survival (OS) rate remains unsatisfactory. Thus,… read more here.
Keywords: chemotherapy; adjuvant chemotherapy; cell; stage ... See more keywords
Abstract 3194: Anti-mesothelin CAR.CIK lymphocytes are effective against ovarian cancer in 3D models of peritoneal carcinomatosis
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3194
Abstract: Peritoneal carcinomatosis (PC) from ovarian cancer (OC) has poor prognosis and is in need for innovative therapies. Such clinical condition displays a composite structure with floating cell aggregates within ascites and solid-like masses invading the… read more here.
Keywords: peritoneal carcinomatosis; cik; ovarian cancer; car ... See more keywords
A single-arm phase Ib study of autologous cytokine-induced killer (CIK) cell immunotherapy in combination with sintilimab plus chemotherapy in patients with advanced non-small cell lung cancer (NSCLC)-CCICC-002.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.2531
Abstract: 2531 Background: Immune checkpoint inhibitors plus chemotherapy had showed benefits for advanced non–small-cell lung cancer (NSCLC) patients without targetable mutations. Autologous cytokine-induced killer (CIK) cells can restore the antitumor immunity to improve patient outcome. Combining… read more here.
Keywords: chemotherapy; cancer; cell; cik cells ... See more keywords
Immunophenotype and antitumor activity of cytokine-induced killer cells from patients with hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0280023
Abstract: Background Cytokine-induced killer (CIK) cells are heterogeneous lymphocytes from human peripheral blood mononucleated cells (PBMCs) co-cultured with several cytokines. The main purpose of this study is to evaluate the functional characteristics and anticancer ability of… read more here.
Keywords: ability; cik; cytokine induced; cik cells ... See more keywords
Phase III randomized trial of autologous cytokine-induced killer cell immunotherapy for newly diagnosed glioblastoma in korea
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.12273
Abstract: Purpose Adoptive cell immunotherapy involves an ex vivo expansion of autologous cytokine-induced killer (CIK) cells before their reinfusion into the host. We evaluated the efficacy and safety of CIK cell immunotherapy with radiotherapy-temozolomide (TMZ) for… read more here.
Keywords: cell immunotherapy; newly diagnosed; immunotherapy; group ... See more keywords
The effect of DC+CIK combined therapy on rat liver cancer model and its modulatory effect on immune functions.
Sign Up to like & getrecommendations! Published in 2018 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201802_14312
Abstract: OBJECTIVE Primary liver cancer is a sort of the most common solid tumors occurred in the digestive system. The incidence and mortality rate maintain at a high level, thus leading to heavy economic and psychological… read more here.
Keywords: cik; cik combined; liver cancer; effect ... See more keywords
Clinical Studies Applying Cytokine-Induced Killer Cells for the Treatment of Renal Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12092471
Abstract: Simple Summary Cytokine-induced killer (CIK) cells are a heterogeneous population of polyclonal T effector cells expanded ex vivo. Here, we updated our last review published in 2012 and provided a synopsis of current 15 clinical… read more here.
Keywords: cik cell; cytokine induced; cik; induced killer ... See more keywords
Integrated Antitumor Activities of Cellular Immunotherapy with CIK Lymphocytes and Interferons against KIT/PDGFRA Wild Type GIST
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810368
Abstract: Gastrointestinal stromal tumors (GISTs) are rare, mesenchymal tumors of the gastrointestinal tract, characterized by either KIT or PDGFRA mutation in about 85% of cases. KIT/PDGFRA wild type gastrointestinal stromal tumors (wtGIST) account for the remaining… read more here.
Keywords: immunotherapy; cik; pdgfra wild; ifn ... See more keywords
Lentiviral delivery of CTLA-4 shRNA improves the expansion of cytokine-induced killer cells and enhances cytotoxic activity in vitro
Sign Up to like & getrecommendations! Published in 2018 at "Oncology Letters"
DOI: 10.3892/ol.2017.7376
Abstract: Cytokine-induced killer (CIK) cells are in vitro-expanded cells harboring potent toxicity against tumor cells. Recently, it was identified that the cytotoxicity and proliferation of CIK cells are restricted by a prolonged CIK cell culture period.… read more here.
Keywords: ctla; cik; shrna; expression ... See more keywords