Cancer Immunotherapy with Cytokine-Induced Killer Cells
Sign Up to like & getrecommendations! Published in 2017 at "Targeted Oncology"
DOI: 10.1007/s11523-017-0489-2
Abstract: AbstractCytokine-induced killer (CIK) cells form under certain stimulation conditions in cultures of peripheral blood mononuclear cells (PBMCs). They are a heterogeneous immune cell population and contain a high percentage of cells with a mixed T-NK… read more here.
Keywords: induced killer; cancer immunotherapy; killer; cik cells ... See more keywords
GCRV 096 VP6 protein and its impacts on GCRV replication with different genotypes in CIK cells
Sign Up to like & getrecommendations! Published in 2018 at "Aquaculture and Fisheries"
DOI: 10.1016/j.aaf.2018.07.005
Abstract: Abstract Grass carp reovirus (GCRV) is the causative agent of grass carp hemorrhagic disease, which has detrimental effects on the grass carp aquaculture industry. There are four known genotypes of GCRV and strains of different… read more here.
Keywords: protein; gcrv; vp6 protein; gcrv 096 ... See more keywords
P09.01 Adoptive cell therapy of hematological malignancies using cytokine-induced killer cells retargeted with monoclonal antibodies
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-itoc7.101
Abstract: Background Cytokine-Induced Killer (CIK) cells are a population of effector cells that represents a promising tool for adoptive cell therapy. They are easily expandable ex-vivo , safe, and exert cytotoxicity against a broad range of… read more here.
Keywords: none; cytokine induced; induced killer; cell ... See more keywords
MMP9-Associated Tumor Stem Cells, CCL1-Silenced Dendritic Cells, and Cytokine-Induced Killer Cells Have a Remarkable Therapeutic Efficacy for Acute Myeloid Leukemia by Activating T Cells
Sign Up to like & getrecommendations! Published in 2023 at "Stem Cells International"
DOI: 10.1155/2023/2490943
Abstract: Purpose Dendritic cells (DC) are specialized antigen-presenting cells, and cytokine-induced killer (CIK) cells have a specific killing activity to a variety of tumors. However, the underlining mechanism and function of DC-CIK cells in acute myeloid… read more here.
Keywords: mmp9 ccl1; cik cells; stem cells;
Abstract 3180: Targeting peptide-loaded-DC CIK cells induce a specific antitumor response
Sign Up to like & getrecommendations! Published in 2019 at "Immunology"
DOI: 10.1158/1538-7445.am2019-3180
Abstract: Currently, immunotherapy has become an effective alternative therapeutic approach for cancers. Cytokine-induced killer (CIK) cells have a higher proliferation rate, increased efficacy with few side-effects, and non- MHC-restricted killing after co-culturing with dendritic cells (DCs).… read more here.
Keywords: loaded cik; peptide loaded; antitumor; cik cells ... See more keywords
Abstract 4141: The induction of iNKT cells and CIK cells toward anti-tumor phenotypes
Sign Up to like & getrecommendations! Published in 2019 at "Immunology"
DOI: 10.1158/1538-7445.am2019-4141
Abstract: Natural killer T (NKT) cells and cytokine-induced killer (CIK) cells contain features of both T cells and NK cells that occasionally brought confusion to several studies. These cells have been reported to possess either anti-tumor… read more here.
Keywords: anti tumor; toward anti; induction inkt; cells cik ... See more keywords
A CTLA-4 blocking strategy based on Nanoboby in dendritic cell-stimulated cytokine-induced killer cells enhances their anti-tumor effects
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DOI: 10.1186/s12885-021-08732-5
Abstract: Background Cytokine-induced killer cells induced with tumor antigen-pulsed dendritic cells (DC-CIK) immunotherapy is a promising strategy for the treatment of malignant tumors. However, itsefficacy isrestricted by the immunosuppression, which is mediated by the cytotoxic T-lymphocyte-associated… read more here.
Keywords: cytokine; ctla; anti tumor; strategy ... See more keywords
A single-arm phase Ib study of autologous cytokine-induced killer (CIK) cell immunotherapy in combination with sintilimab plus chemotherapy in patients with advanced non-small cell lung cancer (NSCLC)-CCICC-002.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.2531
Abstract: 2531 Background: Immune checkpoint inhibitors plus chemotherapy had showed benefits for advanced non–small-cell lung cancer (NSCLC) patients without targetable mutations. Autologous cytokine-induced killer (CIK) cells can restore the antitumor immunity to improve patient outcome. Combining… read more here.
Keywords: chemotherapy; cancer; cell; cik cells ... See more keywords
A comparison of cell-culture plasticwares for effective human cytokine-induced killer cell culture.
Sign Up to like & getrecommendations! Published in 2020 at "Asian Pacific journal of allergy and immunology"
DOI: 10.12932/ap-140720-0913
Abstract: BACKGROUND Cytokine-induced killer (CIK) cells are ex-vivo expanded T cells which present a phenotype of both T and Natural Killer cell properties. OBJECTIVE To compare the proliferation and functional properties of human CIK cells cultured… read more here.
Keywords: killer; cytokine induced; cell; cik cells ... See more keywords
Cytokine-induced killer cell delivery enhances the antitumor activity of oncolytic reovirus
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DOI: 10.1371/journal.pone.0184816
Abstract: Oncolytic viruses (OV) have recently emerged as a promising therapeutic modality in cancer treatment. OV selectively infect and kill tumor cells, while sparing untransformed cells. The direct cytotoxic effects combined with the capacity to trigger… read more here.
Keywords: reovirus; cytokine induced; induced killer; activity ... See more keywords
Cytokine-induced killer cells: A novel treatment for allergic airway inflammation
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0186971
Abstract: The effectiveness of cytokine-induced killer (CIK) cells for treatment of cancers has long been appreciated. Here, we report for the first time that CIK cells can be applied to treat allergic airway inflammation. Adopting from… read more here.
Keywords: cik cells; allergic airway; treatment; airway inflammation ... See more keywords