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Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12020405
Abstract: Oxidative stress (OS) on tissues is a major pathological insult leading to elevated intraocular pressure (IOP) and primary open-angle glaucoma (POAG). Aqueous humor (AH) produced by the non-pigmentary ciliary epithelium (NPCE) drains out via the…
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Keywords:
open angle;
angle glaucoma;
ciliary epithelium;
primary open ... See more keywords
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1
Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021673
Abstract: Previously, we reported a mechanosensitive ion channel, TRPV4, along with functional connexin hemichannels on the basolateral surface of the ocular nonpigmented ciliary epithelium (NPE). In the lens, TRPV4-mediated hemichannel opening is part of a feedback…
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Keywords:
stretch;
nonpigmented ciliary;
ciliary epithelium;
atp release ... See more keywords
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Published in 2021 at "Pharmaceuticals"
DOI: 10.3390/ph14090858
Abstract: Primary open-angle glaucoma is established by the disruption of trabecular meshwork (TM) function. The disruption leads to increased resistance to the aqueous humor (AH), generated by the non-pigmented ciliary epithelium (NPCE). Extracellular vesicles (EVs) participate…
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Keywords:
ciliary epithelium;
extracellular vesicles;
trabecular meshwork;
smad7 sirna ... See more keywords