RABL4/IFT27 in a nucleotide‐independent manner promotes phospholipase D ciliary retrieval via facilitating BBSome reassembly at the ciliary tip
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DOI: 10.1002/jcp.30945
Abstract: Certain ciliary transmembrane and membrane‐associated signaling proteins export from cilia as intraflagellar transport (IFT) cargoes in a BBSome‐dependent manner. Upon reaching the ciliary tip via anterograde IFT, the BBSome disassembles before being reassembled to form… read more here.
Keywords: bbsome reassembly; tip; ciliary tip; ift27 nucleotide ... See more keywords
Phosphorylation-induced SUMOylation promotes Ulk4 condensation at the ciliary tip to transduce Hedgehog signal
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DOI: 10.1242/jcs.263695
Abstract: ABSTRACT Hedgehog (Hh) signaling controls embryonic development and adult tissue homeostasis through the Gli family of transcription factors. In vertebrates, Hh signal transduction depends on the primary cilium, where Gli proteins are thought to be… read more here.
Keywords: sumoylation; tip; phosphorylation; ciliary tip ... See more keywords
Three-dimensional beating pattern of the ciliary tip in the live ciliate Tetrahymena
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DOI: 10.1242/jcs.264027
Abstract: ABSTRACT Ciliates utilise motile cilia, which are highly dynamic organelles protruding from the cell surface, to swim helically in a three-dimensional (3D) space. The 3D nature of their swimming behaviour and rapid ciliary beatings make… read more here.
Keywords: tip live; tip; ciliary tip; cell ... See more keywords