Ciliogenesis associated kinase 1: targets and functions in various organ systems
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DOI: 10.1002/1873-3468.13600
Abstract: Ciliogenesis associated kinase 1 (CILK1) was previously known as intestinal cell kinase because it was cloned from that origin. However, CILK1 is now recognized as a widely expressed and highly conserved serine/threonine protein kinase. Mutations… read more here.
Keywords: ciliogenesis associated; associated kinase; cilk1; kinase targets ... See more keywords
Modulation of Primary Cilia by Alvocidib Inhibition of CILK1
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DOI: 10.3390/ijms23158121
Abstract: The primary cilium provides cell sensory and signaling functions. Cilia structure and function are regulated by ciliogenesis-associated kinase 1 (CILK1). Ciliopathies caused by CILK1 mutations show longer cilia and abnormal Hedgehog signaling. Our study aimed… read more here.
Keywords: cilk1; modulation primary; inhibition cilk1; primary cilia ... See more keywords