Artificial Microvesicles Isolated from Mesenchymal Stem Cells with IL2 Overexpression Activate CD8+ T-Killers to Kill Triple Negative Breast Cancer Cells
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DOI: 10.1182/blood-2020-133934
Abstract: Almost all human cells release extracellular vesicles (EVs) participating in intercellular communication. EVs are rounded structures surrounded by the cytoplasmic membrane, which embody cytoplasmic contents of the parent cells. Since the orientation of surface receptors… read more here.
Keywords: pbmcs; cimvs il2; mda 231; cimvs ... See more keywords
Biomimetic Membrane Vesicles: Evaluation of Inflammatory Response In Vivo
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DOI: 10.1182/blood-2020-135826
Abstract: Introduction: Biomimetic membrane vesicles are produced from live cells using cytochalasin B which disrupts the structure of the cytoskeleton and facilitate generation of membrane vesicles under subsequent vortexing. Membrane vesicles are pinched off from the… read more here.
Keywords: biomimetic membrane; immunogenicity; cimvs; membrane vesicles ... See more keywords