Abstract 4965: Targeting the mitotic kinesin, KIF18A, in chromosomally unstable cancers
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DOI: 10.1158/1538-7445.am2023-4965
Abstract: Background: Chromosome instability (CIN), characterized by frequent and ongoing loss or gain of chromosome number, is commonly observed in tumor cells. Although long recognized as a vulnerability of cancer cells, potential CIN-selective therapeutic targets have… read more here.
Keywords: small molecule; mitotic kinesin; kif18a; kinesin kif18a ... See more keywords