Synthesis of chiral polyurethanes of cinchona alkaloids for the enantioselective synthesis in asymmetric catalysis
Sign Up to like & getrecommendations! Published in 2019 at "Catalysis Communications"
DOI: 10.1016/j.catcom.2018.09.010
Abstract: Abstract Chiral polyurethanes of cinchona alkaloid were synthesized via repetitive Mizoroki-Heck (MH) coupling reaction. The Pd-catalyzed polycondensation of cinchona urethane dimers and aromatic diiodides afforded the chiral polyurethanes. The chiral polyurethane bearing free OH group… read more here.
Keywords: synthesis; cinchona alkaloids; chiral polyurethanes; synthesis chiral ... See more keywords
Role of Cinchona Alkaloids in the Enantio- and Diastereoselective Synthesis of Axially Chiral Compounds
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DOI: 10.1021/acs.accounts.2c00515
Abstract: Conspectus Asymmetric synthesis using organic catalysts has evolved since it was first realized and defined. Nowadays, it can be considered a valid alternative to transition metal catalysis for synthesizing chiral molecules. According to the literature,… read more here.
Keywords: role cinchona; cinchona alkaloids; synthesis; desymmetrization ... See more keywords
Multicomponent crystals of an artemisinin derivative and cinchona alkaloids for use as antimalarial drugs
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DOI: 10.1039/d1ce00974e
Abstract: Multicomponent crystals of an artemisinin derivative and cinchona alkaloids were produced, combining two major types of antimalaria drugs with unique hydrogen bond interactions. These salts demonstrate a new category of antimalarial pharmaceuticals. read more here.
Keywords: multicomponent crystals; cinchona alkaloids; derivative cinchona; artemisinin derivative ... See more keywords
New Members of the Cinchona Alkaloids Family: Assembly of the Triazole Heterocycle at the 6′ Position
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DOI: 10.3390/molecules26113357
Abstract: The substance class of the well-known Cinchona alkaloids is widened by 6′-Amino-cinchonine and 6′-Amino-cinchonidine, novel compounds which incorporate a primary amino function in the quinolinic ring system. These key intermediates open the field for a… read more here.
Keywords: cinchona alkaloids; family assembly; new members; position ... See more keywords