Visible-Light-Mediated Decarboxylative Thiocyanation of Cinnamic acids: An Efficient Photocatalytic Approach to the Synthesis of (E)-Vinyl Thiocyanates
Sign Up to like & getrecommendations! Published in 2020 at "Catalysis Letters"
DOI: 10.1007/s10562-020-03414-6
Abstract: A simple and novel methodology for the synthesis of vinyl thiocyanates from decarboxylative cross-coupling reaction of cinnamic acids with KSCN under the synergistic interactions of visible light irradiation, Cs2CO3, Rose Bengal as the photocatalyst and… read more here.
Keywords: thiocyanation cinnamic; synthesis vinyl; light mediated; visible light ... See more keywords
One pot synthesis of α,β-epoxy ketones by oxidative coupling of methyl arenes with cinnamic acids involving C(sp 3 )―H activation and decarboxylative strategy
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.04.025
Abstract: Abstract A new one pot oxidative coupling of methyl arenes with cinnamic acids has been developed for the synthesis of α,β-epoxy ketones using MnO 2 /TBHP combination. The process involves a co-existing C(sp 3 )―H… read more here.
Keywords: coupling methyl; arenes cinnamic; oxidative coupling; one pot ... See more keywords
Copper-catalyzed oxidative decarboxylative alkylation of cinnamic acids with 4-alkyl-1,4-dihydropyridines.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc06401g
Abstract: We have developed a new oxidative decarboxylation of cinnamic acids with 4-alkyl-1,4-dihydropyridines to construct C(sp3)-C(sp2) bonds in the presence of copper catalyst and dicumyl peroxide (DCP). A variety of internal alkenes have been obtained with… read more here.
Keywords: copper catalyzed; acids alkyl; alkyl dihydropyridines; cinnamic acids ... See more keywords
Novel synthesis of 1,2-diaza-1,3-dienes with potential biological activity from cinnamic acids and diazonium salts of anilines
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DOI: 10.1039/d2ra07515f
Abstract: Cinnamic acids are an important class of phenolic compounds, which have many beneficial effects on human health but are also interesting synthetic intermediates thanks to the presence of several reactive sites. While studying the reactivity… read more here.
Keywords: diaza dienes; diazonium salts; cinnamic acids; biological activity ... See more keywords
NIS-initiated photo-induced oxidative decarboxylative sulfoximidation of cinnamic acids.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc00142c
Abstract: N-Iodosuccinimide catalyzed, visible-light-induced oxidative decarboxylative cross-coupling between cinnamic acids and NH-sulfoximines is presented. This strategy results in the formation of α-keto-N-acyl sulfoximines via the construction of two new CO bonds and one C-N bond. The… read more here.
Keywords: initiated photo; cinnamic acids; photo induced; nis initiated ... See more keywords
Cinnamic acids as promising bioactive compounds for cancer therapy by targeting MAPK3: a computational simulation study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Complementary and Integrative Medicine"
DOI: 10.1515/jcim-2023-0046
Abstract: Abstract Objectives Mitogen-activated protein kinase-3 (MAPK3) is the upstream regulator in the MAPK cascade and is involved in many critical signaling pathways and biological processes, such as cell proliferation, survival, and apoptosis. MAPK3 overexpression is… read more here.
Keywords: mapk3; cinnamic acids; site; acid ... See more keywords
Multi-Target Cinnamic Acids for Oxidative Stress and Inflammation: Design, Synthesis, Biological Evaluation and Modeling Studies
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DOI: 10.3390/molecules24010012
Abstract: Inflammation is a complex phenomenon that results as a healing response of organisms to different factors, exerting immune signaling, excessive free radical activity and tissue destruction. Lipoxygenases and their metabolites e.g., LTB4, are associated with… read more here.
Keywords: lipoxygenase; design; inflammation; target cinnamic ... See more keywords