Cinnarizine as an alternative recommendation for migraine prophylaxis: a narrative review
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DOI: 10.1080/14737175.2020.1787834
Abstract: ABSTRACT Introduction Despite the available prophylactic and acute drugs for migraine management, this disabling disorder remains undertreated especially among pediatrics. In this review, the authors aim at assessing the preventive role cinnarizine plays in treating… read more here.
Keywords: migraine; migraine prophylaxis; cinnarizine; review ... See more keywords
An Insight into Eudragit S100 Preserving Mechanism of Cinnarizine Supersaturation.
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DOI: 10.1208/s12249-022-02223-x
Abstract: Generally, supersaturation of weakly basic drug solution in the gastrointestinal tract can be followed by precipitation, and this can compromise the bioavailability of drugs. The purpose of this study was to evaluate the effect of… read more here.
Keywords: preserving mechanism; cinnarizine supersaturation; cinnarizine; eudragit s100 ... See more keywords
Formulation and Characterization of Cinnarizine Targeted Aural Transfersomal Gel for Vertigo Treatment: A Pharmacokinetic Study on Rabbits
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DOI: 10.2147/ijn.s258764
Abstract: Introduction and Aim Cinnarizine is indicated orally for treating vertigo associated with Ménière’s syndrome and has a local anesthetic effect as well. The present study aims to develop an aural Cinnarizine mucoadhesive transfersomal gel to… read more here.
Keywords: drug; study; cinnarizine; pharmacokinetic study ... See more keywords
Validated Chromatographic Methods for Simultaneous Estimation of Cinnarizine in Binary Mixture with Domperidone and Paracetamol in Tablets
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DOI: 10.2174/1573412914666180307154921
Abstract: Cinnarizine, an antihistaminic drug, is commonly formulated in combination with domperidone and with paracetamol for treatment and prevention of motion sickness and migraine.The aim of this work was to develop new, simple, precise and selective… read more here.
Keywords: domperidone paracetamol; cinnarizine; chromatographic methods; method ... See more keywords