Articles with "cinobufotalin" as a keyword



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Combination of TPF regimen and cinobufotalin inhibits proliferation and induces apoptosis in human hypopharyngeal and laryngeal squamous cell carcinoma cells

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Published in 2019 at "OncoTargets and therapy"

DOI: 10.2147/ott.s185428

Abstract: Background Hypopharyngeal squamous cell carcinoma and laryngeal squamous cell carcinoma have a potential risk of metastasis and local recurrence. It is urgent to determine novel effective therapy. Methods UMSCC5 and FADU cells were treated with… read more here.

Keywords: cell carcinoma; combination; cinobufotalin; cell ... See more keywords
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Cinobufotalin induces ferroptosis to suppress lung cancer cell growth by lncRNA LINC00597\hsa-miR-367-3p\TFRC pathway via resibufogenin.

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Published in 2022 at "Anti-cancer agents in medicinal chemistry"

DOI: 10.2174/1871520622666221010092922

Abstract: Background Lung cancer is the leading cause of cancer-associated death and the first most diagnosed cancer in the world. More than 2 million new cases are diagnosed and 1.6 million people die due to lung… read more here.

Keywords: lung cancer; cancer; hsa mir; cinobufotalin ... See more keywords
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The Potential Mechanisms of Cinobufotalin Treating Colon Adenocarcinoma by Network Pharmacology

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.934729

Abstract: Network pharmacology, as a novel way using bioinformatics to explore drug targets and interactions in cancer, broadens our understanding of drug action, thereby facilitating drug discovery. Here, we utilized network pharmacology to explore the role… read more here.

Keywords: pharmacology; coad; network pharmacology; cinobufotalin ... See more keywords
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Differentially expressed gene profile and relevant pathways of the traditional Chinese medicine cinobufotalin on MCF-7 breast cancer cells

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Published in 2019 at "Molecular Medicine Reports"

DOI: 10.3892/mmr.2019.10062

Abstract: Cinobufotalin is a chemical compound extracted from the skin of dried bufo toads that may have curative potential for certain malignancies through different mechanisms; however, these mechanisms remain unexplored in breast cancer. The aim of… read more here.

Keywords: medicine; cancer cells; cinobufotalin; breast cancer ... See more keywords