Articles with "cinv" as a keyword



Evaluation of chemotherapy-induced nausea and vomiting in pediatric patients with high-grade glioma treated with lomustine—a case series

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Published in 2024 at "Supportive Care in Cancer"

DOI: 10.1007/s00520-024-08474-7

Abstract: Although lomustine has been used as a chemotherapeutic agent for decades, no recommendation on appropriate chemotherapy-induced nausea and vomiting (CINV) prophylaxis is available. As CINV is considered one of the most bothersome side effects of… read more here.

Keywords: case series; grade glioma; high grade; treated lomustine ... See more keywords
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Evaluation of Adherence to Antiemetic Treatment Guidelines in Patients With Chemotherapy-Induced Nausea and Vomiting in Teaching Hospitals in Tehran

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Published in 2020 at "Journal of Cancer Education"

DOI: 10.1007/s13187-020-01689-2

Abstract: The present study evaluated adherence to antiemetic guidelines for prevention and treatment of chemotherapy-induced nausea and vomiting (CINV) in four tertiary university teaching hospitals in Tehran. This prospective observational study enrolled 382 adult patients on… read more here.

Keywords: category; adherence antiemetic; induced nausea; cinv ... See more keywords

Chemotherapy-induced nausea and vomiting (CINV) in 190 colorectal cancer patients: a prospective registration study by the CINV study group of Japan

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Published in 2017 at "Expert Opinion on Pharmacotherapy"

DOI: 10.1080/14656566.2017.1317746

Abstract: ABSTRACT Objectives: Chemotherapy is an indispensable therapeutic approach for colorectal cancer both in the adjuvant and metastatic setting. Although chemotherapy-induced nausea and vomiting (CINV) is one of the most crucial adverse events, many aspects of… read more here.

Keywords: chemotherapy; colorectal cancer; study; cinv ... See more keywords

Granisetron in the treatment of chemotherapy-induced nausea and vomiting (CINV) – is there still a role after comparison with palonosetron?

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Published in 2017 at "Expert Opinion on Pharmacotherapy"

DOI: 10.1080/14656566.2017.1342809

Abstract: ABSTRACT Introduction: Chemotherapy-induced nausea and vomiting (CINV) has a negative impact on the lives of subjects receiving chemotherapy. In 2009, the second generation 5-HT3-receptor antagonist, palonosetron, which is longer-acting than granisetron, was shown, as part… read more here.

Keywords: induced nausea; cinv; chemotherapy induced; palonosetron ... See more keywords

Efficacy of NEPA for prevention of chemotherapy-induced nausea and vomiting in cancer patients receiving highly emetogenic chemotherapy and usefulness of adding olanzapine for grade 2 or higher emesis

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Published in 2025 at "Medicine"

DOI: 10.1097/md.0000000000043210

Abstract: NEPA has demonstrated superiority in preventing chemotherapy-induced nausea and vomiting (CINV) compared to palonestron and non-inferiority compared to aprepitant/granisetron. However, despite the application of NEPA in previous studies, grade (Gr) 2 or higher CINV was… read more here.

Keywords: higher cinv; cancer patients; cinv; adding olanzapine ... See more keywords

5HT3RA plus dexamethasone plus aprepitant for controlling delayed chemotherapy‐induced nausea and vomiting in colorectal cancer

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Published in 2020 at "Cancer Science"

DOI: 10.1111/cas.14757

Abstract: Delayed chemotherapy‐induced nausea and vomiting (CINV) is not well controlled in colorectal cancer (CRC) patients undergoing oxaliplatin (L‐OHP)‐based chemotherapy. Whether neurokinin‐1 receptor antagonist addition to a first‐generation 5HT3 antagonist (1st 5‐HT3RA) and dexamethasone (DEX) is… read more here.

Keywords: chemotherapy; palo; dex; palo dex ... See more keywords

A unique schedule of palonosetron, ondansetron, and dexamethasone for the prevention of delayed nausea and vomiting in patients receiving myeloablative chemotherapy

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Published in 2018 at "Journal of Oncology Pharmacy Practice"

DOI: 10.1177/1078155218790345

Abstract: Myeloablative chemotherapy administered prior to autologous stem cell transplantation (auto-SCT) is associated with a significant amount of chemotherapy-induced nausea and vomiting (CINV). We conducted a phase II trial to assess the safety, efficacy, and impact… read more here.

Keywords: chemotherapy; cinv; myeloablative chemotherapy; quality life ... See more keywords

Extended aprepitant in control of delayed emesis during induction chemotherapy for acute myeloid leukaemia – an multicentric, investigator-initiated, open label randomized controlled trial

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Published in 2025 at "Blood"

DOI: 10.1182/blood-2025-1681

Abstract: IntroductionThe management of chemotherapy induced nausea and vomiting (CINV) during intensive induction chemotherapy for acute myeloid leukaemia (AML) is often not optimal due to prolonged infusion of chemotherapy over 7 days as well as omission… read more here.

Keywords: control; cinv; chemotherapy; extended aprepitant ... See more keywords

An open-label randomized trial comparing addition of olanzapine 5 mg versus olanzapine 10 mg as anti-emetic to standard anti-emetic regime for doxorubicin or epirubicin and cyclophosphamide in breast cancer.

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Published in 2024 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2024.42.16_suppl.e12531

Abstract: e12531 Background: Chemotherapy-induced nausea and vomiting (CINV) is an important therapy related side effects in the treatment of malignancies. Breast cancer patients receive a highly-emetogenic chemotherapy with Doxorubicin or Epirubicin and Cyclophosphamide. The addition of… read more here.

Keywords: cancer; trial; cinv; anti emetic ... See more keywords

Comprehensive gut microbiota and metabolomics combined with network pharmacology reveal the effects of acupuncture treatment for chemotherapy-induced nausea and vomiting

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Published in 2025 at "Translational Gastroenterology and Hepatology"

DOI: 10.21037/tgh-24-35

Abstract: Background Chemotherapy-induced nausea and vomiting (CINV) significantly impact cancer patients’ quality of life. Traditional pharmacological treatments often have limited effectiveness and can cause adverse effects. Acupuncture, a key practice in traditional Chinese medicine (TCM), shows… read more here.

Keywords: effects acupuncture; pharmacology; cinv; gut microbiota ... See more keywords
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Clinical Observation of Gene Polymorphism of Olanzapine or Aprepitant in Prevention of CINV

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Published in 2021 at "Pharmacogenomics and Personalized Medicine"

DOI: 10.2147/pgpm.s317229

Abstract: Objective The present study aims to investigate the correlation between the gene polymorphisms of the multidrug resistance protein 1 (ABCB1), the intron region of transcriptional factor (GTF2E1) and catechol-O-methyltransferase (COMT), dopamine receptor (DRD2), and the… read more here.

Keywords: cinv; gene; olanzapine aprepitant; olanzapine group ... See more keywords