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Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.01.022
Abstract: The ascidian Ciona intestinalis has a high regeneration capacity that enables the regeneration of artificially removed primordial germ cells (PGCs) from somatic cells. We utilized PGC regeneration to establish efficient methods of germ line mutagenesis…
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Keywords:
ciona;
mutagenesis;
regeneration;
germ cell ... See more keywords
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Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.10.010
Abstract: Electroporation-based assays were used to test whether the myogenic regulatory factor (MRF) of Ciona intestinalis (CiMRF) interferes with endogenous developmental programs, and to evaluate the importance of its unusual N-terminus for muscle development. We found…
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Keywords:
ciona;
regulatory factor;
mrf;
activity ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0180227
Abstract: The nervous system of ascidians is an excellent model system to provide insights into the evolutionary process of the chordate nervous system due to their phylogenetic positions as the sister group of vertebrates. However, the…
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Keywords:
ciona;
system;
nervous system;
innervation ... See more keywords
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Published in 2022 at "Zoological Science"
DOI: 10.2108/zs210102
Abstract: Gene/transcript model sets predicted from decoded genome sequences are an important resource for a wide range of biological studies. Accuracy of gene models is therefore critical for deducing accurate conclusions. Computationally predicted models are sometimes…
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Keywords:
model set;
gene transcript;
ciona;
transcript model ... See more keywords
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Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.868143
Abstract: To identify potential regions of the voltage-sensing domain that could shift the voltage sensitivity of Ciona intestinalis based Genetically Encoded Voltage Indicators (GEVIs), we aligned the amino acid sequences of voltage-gated sodium channels from different…
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Keywords:
amino acids;
ciona;
voltage sensing;
voltage ... See more keywords
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Published in 2021 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2021.784649
Abstract: Conserved transcription factors termed “terminal selectors” regulate neuronal sub-type specification and differentiation through combinatorial transcriptional regulation of terminal differentiation genes. The unique combinations of terminal differentiation gene products in turn contribute to the functional identities…
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Keywords:
ciona;
motor ganglion;
cholinergic locus;
cholinergic ... See more keywords
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Published in 2021 at "Marine Drugs"
DOI: 10.3390/md19020111
Abstract: Ciona molecule against microbes-A24 (CiMAM) isolated from the marine chordate Ciona intestinalis is an antimicrobial peptide. To generate CiMAM-expressing transgenic Bacillus subtilis, we constructed a plasmid expressing recombinant CiMAM (rCiMAM) and introduced it into B.…
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Keywords:
ciona;
marine;
ciona intestinalis;
antimicrobial peptide ... See more keywords