Translating the measurement of hERG kinetics and drug block for CiPA to a high throughput platform.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of pharmacological and toxicological methods"
DOI: 10.2139/ssrn.4065593
Abstract: The Comprehensive in vitro Proarrhythmic Assay (CiPA) has promoted use of in silico models of drug effects on cardiac repolarization to improve proarrhythmic risk prediction. These models contain a pharmacodynamic component describing drug binding to… read more here.
Keywords: cipa; high throughput; block; drug ... See more keywords
CipA mediates complement resistance of Acinetobacter baumannii by formation of a factor I-dependent quadripartite assemblage
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.942482
Abstract: Multidrug-resistant Acinetobacter baumannii is known to be one of the leading pathogens that cause severe nosocomial infections. To overcome eradication by the innate immune system during infection, A. baumannii developed a number of immune evasion… read more here.
Keywords: factor dependent; factor; acinetobacter baumannii; cipa ... See more keywords
Comparison of CIPA Nutritional Screening with GLIM Criteria for Malnutrition, Prognostic Evolution, and Association with Phase Angle in Hospitalized Patients
Sign Up to like & getrecommendations! Published in 2024 at "Nutrients"
DOI: 10.3390/nu16213652
Abstract: Background: Hospital malnutrition has high prevalence and is associated with worse clinical outcomes. The lack of standardized nutritional screening prompted the creation of the CIPA screening tool. Several studies have shown that the phase angle… read more here.
Keywords: glim; phase angle; clinical outcomes; glim criteria ... See more keywords