The application of in silico experimental model in the assessment of ciprofloxacin and levofloxacin interaction with main SARS-CoV-2 targets: S-, E- and TMPRSS2 proteins, RNA-dependent RNA polymerase and papain-like protease (PLpro)—preliminary molecular docking analysis
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DOI: 10.1007/s43440-021-00282-8
Abstract: Background The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified at the end of 2019. Despite growing understanding of SARS-CoV-2 in virology as well as many molecular studies, except remdesivir, no specific anti-SARS-CoV-2… read more here.
Keywords: protease; rna polymerase; proteins rna; ciprofloxacin levofloxacin ... See more keywords
[In vitro activity of delafloxacin against bacterial isolates from osteoarticular and skin infections in Buenos Aires, Argentina].
Sign Up to like & getrecommendations! Published in 2021 at "Revista Argentina de microbiologia"
DOI: 10.1016/j.ram.2021.02.012
Abstract: In vitro activities of delafloxacin, ciprofloxacin and levofloxacin were evaluated by epsilometric and disk diffusion methods against 181 bacterial isolates recovered from bone and skin infections. Isolates included were 84 Staphylococcus aureus (40 MRSA and… read more here.
Keywords: delafloxacin ciprofloxacin; vitro activity; cns; bacterial isolates ... See more keywords
Dry powders for the inhalation of ciprofloxacin or levofloxacin combined with a mucolytic agent for cystic fibrosis patients
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DOI: 10.1080/03639045.2017.1318902
Abstract: Abstract Objective: This study aimed to design and characterize an inhalable dry powder of ciprofloxacin or levofloxacin combined with the mucolytics acetylcysteine and dornase alfa for the management of pulmonary infections in patients with cystic… read more here.
Keywords: dry powders; cystic fibrosis; levofloxacin combined; ciprofloxacin ... See more keywords
Pharmacodynamics of Finafloxacin, Ciprofloxacin, and Levofloxacin in Serum and Urine against TEM- and SHV-Type Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae Isolates from Patients with Urinary Tract Infections
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DOI: 10.1128/aac.02446-16
Abstract: ABSTRACT The pharmacodynamics of finafloxacin, ciprofloxacin, and levofloxacin against extended-spectrum-β-lactamase (ESBL)-producing Enterobacteriaceae isolates were compared. Since quinolones lose activity in acidic media, and particularly in urine, their activities were tested in parallel under conventional conditions… read more here.
Keywords: levofloxacin; artificial urine; ciprofloxacin levofloxacin; type ... See more keywords
Antidepressant activity of ciprofloxacin and levofloxacin by using tail suspension test in Swiss albino mice on chronic administration
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Parallel Programming"
DOI: 10.18231/2393-9087.2018.0026
Abstract: Introduction: Depression is evidenced by decreased mood and reduced activity that can affect person's thoughts, behavior, feelings, and also sense of well-being in the society. Use of long term antidepressant agent pose a significant adverse… read more here.
Keywords: antidepressant activity; ciprofloxacin levofloxacin; activity; test ... See more keywords
Comparing the Synergistic and Antagonistic Interactions of Ciprofloxacin and Levofloxacin Combined with Rifampin against Drug-Resistant Staphylococcus aureus: A Time–Kill Assay
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DOI: 10.3390/antibiotics12040711
Abstract: Background: Treatment of device-related infections by drug-resistant Staphylococcus aureus can be challenging, and combination therapy has been proposed as a potential solution. We compared the effectiveness of levofloxacin–rifampin and ciprofloxacin–rifampin combinations in killing methicillin-resistant S.… read more here.
Keywords: levofloxacin; antagonistic interactions; rifampin; ciprofloxacin levofloxacin ... See more keywords
Ciprofloxacin and Levofloxacin as Potential Drugs in Genitourinary Cancer Treatment—The Effect of Dose–Response on 2D and 3D Cell Cultures
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DOI: 10.3390/ijms222111970
Abstract: Introduction: Introducing new drugs for clinical application is a very difficult, long, drawn-out, and costly process, which is why drug repositioning is increasingly gaining in importance. The aim of this study was to analyze the… read more here.
Keywords: cell lines; cytotoxic effect; effect; ciprofloxacin levofloxacin ... See more keywords