Overexpression of Circ-Astn1 Suppresses Hyperglycemia-Induced Endothelial Cell Damage via the miR-138-5p/SIRT1 Axis
Sign Up to like & getrecommendations! Published in 2025 at "Current Medical Science"
DOI: 10.1007/s11596-025-00011-9
Abstract: To elucidate the regulatory mechanism of circRNAs in diabetic retinopathy. Next-generation sequencing (NGS) was employed to identify circRNAs that are abnormally expressed in endothelial progenitor cells (EPCs) under hyperglycemia (HG) conditions. The regulatory mechanism and… read more here.
Keywords: mir 138; induced endothelial; circ astn1; overexpression ... See more keywords
The Expression of Circ-Astn1 Inhibits High Glucose Induced Endothelial Progenitor Cell Dysfunction by Activating Autophagy
Sign Up to like & getrecommendations! Published in 2024 at "Endocrine Research"
DOI: 10.1080/07435800.2024.2365887
Abstract: ABSTRACT Background Diabetes mellitus (DM) and complications such as chronic kidney disease and cardiovascular symptoms pose a substantial public health burden. Increasing studies have shown that circular RNAs (circRNAs) regulate many gene expressions that are… read more here.
Keywords: circ astn1; induced endothelial; endothelial progenitor; cell ... See more keywords