P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian β-cell failure
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DOI: 10.7554/elife.75132
Abstract: The mammalian circadian clock drives daily oscillations in physiology and behavior through an autoregulatory transcription feedback loop present in central and peripheral cells. Ablation of the core clock within the endocrine pancreas of adult animals… read more here.
Keywords: small molecule; cell; cell failure; circadian cell ... See more keywords