Associations between circadian disruption and cardiometabolic disease risk: A review
Sign Up to like & getrecommendations! Published in 2023 at "Obesity"
DOI: 10.1002/oby.23666
Abstract: The human circadian system plays a vital role in many physiological processes, and circadian rhythms are found in virtually all tissues and organs. The disruption of circadian rhythms may lead to adverse health outcomes. Evidence… read more here.
Keywords: health; associations circadian; circadian disruption; circadian rhythms ... See more keywords
Melatonin, an ubiquitous metabolic regulator: functions, mechanisms and effects on circadian disruption and degenerative diseases
Sign Up to like & getrecommendations! Published in 2020 at "Reviews in Endocrine and Metabolic Disorders"
DOI: 10.1007/s11154-020-09570-9
Abstract: The last four decades, we assist to an increasing scientific interest on melatonin, a circadian hormone, a metabolic regulator which influences not only plants’ metabolism and their defense against pathogens but mostly the animals and… read more here.
Keywords: metabolic regulator; diseases melatonin; circadian disruption; degenerative diseases ... See more keywords
Mealtime: A circadian disruptor and determinant of energy balance?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroendocrinology"
DOI: 10.1111/jne.12886
Abstract: Circadian rhythms play a critical role in the physiological processes involved in energy metabolism and energy balance (EB). A large array of metabolic processes, including the expression of many energy‐regulating endocrine hormones, display temporal rhythms… read more here.
Keywords: circadian disruption; energy; rhythms; energy balance ... See more keywords
0086 Shiftwork, circadian disruption and breast cancer: a first application of the chronobiological theory and practical challenges within the australian bcee study
Sign Up to like & getrecommendations! Published in 2017 at "Occupational and Environmental Medicine"
DOI: 10.1136/oemed-2017-104636.64
Abstract: Background In 2007, the International Agency for Research on Cancer [IARC] classified shiftwork involving circadian disruption [CD] as probably carcinogenic to humans. We hypothesised that CD occurs if individuals work during their preferred sleep time… read more here.
Keywords: cancer; circadian disruption; shiftwork; breast cancer ... See more keywords
Circadian disruption via timing of food availability contributes to renal fibrogenesis in male, but not female mice
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733614
Abstract: Previous work from our lab showed that restricting food to the lights-on (inactive) period for less than one week causes circadian misalignment blood pressure and kidney excretory rhythms. Since circadian disruption increases risk of cardiometabolic… read more here.
Keywords: circadian disruption; food; physiology; male female ... See more keywords
Exposure to Circadian Disruption During Adolescence Interacts With a Genetic Risk Factor to Modify Schizophrenia-relevant Behaviors in a Sex-dependent Manner
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biological Rhythms"
DOI: 10.1177/07487304221125363
Abstract: DTNBP1 is a gene associated with schizophrenia. Postmortem studies found a reduced expression of DTNBP1 in regions associated with schizophrenia in patients’ brains. Sandy (Sdy) mice have a loss-of-function mutation in Dtnbp1 gene, resulting in… read more here.
Keywords: circadian disruption; sdy mice; disruption; adolescence ... See more keywords
Circadian disruption promotes tumor growth by anabolic host metabolism; experimental evidence in a rat model
Sign Up to like & getrecommendations! Published in 2017 at "BMC Cancer"
DOI: 10.1186/s12885-017-3636-3
Abstract: BackgroundLight at night creates a conflicting signal to the biological clock and disrupts circadian physiology. In rodents, light at night increases the risk to develop mood disorders, overweight, disrupted energy metabolism, immune dysfunction and cancer.… read more here.
Keywords: circadian disruption; tumor; metabolism; host ... See more keywords
Chronic Sleep Restriction While Minimizing Circadian Disruption Does Not Adversely Affect Glucose Tolerance
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.764737
Abstract: Insufficient sleep, which has been shown to adversely affect metabolism, is generally associated with prolonged exposure to artificial light at night, a known circadian disruptor. There is growing evidence suggesting that circadian disruption adversely affects… read more here.
Keywords: circadian disruption; sleep restriction; disruption; disruption adversely ... See more keywords
Circadian Disruption and Consequences on Innate Immunity and Inflammatory Response
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232213722
Abstract: Circadian rhythms control almost all aspects of physiology and behavior, allowing temporal synchrony of these processes between each other, as well as with the external environment. In the immune system, daily rhythms of leukocyte functions… read more here.
Keywords: circadian disruption; disruption; innate immunity; disruption consequences ... See more keywords
Circadian Disruption and Mental Health: The Chronotherapeutic Potential of Microbiome-Based and Dietary Strategies
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24087579
Abstract: Mental illness is alarmingly on the rise, and circadian disruptions linked to a modern lifestyle may largely explain this trend. Impaired circadian rhythms are associated with mental disorders. The evening chronotype, which is linked to… read more here.
Keywords: disruption mental; circadian disruption; gut microbiota; circadian rhythms ... See more keywords