Derailed peripheral circadian genes in polycystic ovary syndrome patients alters peripheral conversion of androgens synthesis.
Sign Up to like & getrecommendations! Published in 2022 at "Human reproduction"
DOI: 10.1093/humrep/deac139
Abstract: STUDY QUESTION Do circadian genes exhibit an altered profile in peripheral blood mononuclear cells (PBMCs) of polycystic ovary syndrome (PCOS) patients and do they have a potential role in androgen excess? SUMMARY ANSWER Our findings… read more here.
Keywords: expression; circadian genes; pcos; clock genes ... See more keywords
Investigating the relationship between melatonin patterns and methylation in circadian genes among day shift and night shift workers
Sign Up to like & getrecommendations! Published in 2022 at "Occupational and Environmental Medicine"
DOI: 10.1136/oemed-2021-108111
Abstract: Objectives Mechanisms underlying the carcinogenicity of night shift work remain uncertain. One compelling yet understudied cancer mechanism may involve altered DNA methylation in circadian genes due to melatonin secretion patterns. The objective of this study… read more here.
Keywords: methylation; shift workers; night shift; circadian genes ... See more keywords
Advances in the Study of Circadian Genes in Non-Small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Integrative Cancer Therapies"
DOI: 10.1177/15347354221096080
Abstract: Circadian genes regulate several physiological functions such as circadian rhythm and metabolism and participate in the cytogenesis and progression of various malignancies. The abnormal expression of these genes in non-small cell lung cancer (NSCLC) is… read more here.
Keywords: lung cancer; non small; genes non; circadian genes ... See more keywords
Addiction and the Role of Circadian Genes.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of studies on alcohol and drugs"
DOI: 10.15288/jsad.2017.78.645
Abstract: OBJECTIVE In mammals, intimate interactions exist between the circadian system and other molecular systems, and mounting evidence is suggesting that these relationships may affect substance use disorders. Research in preclinical models supports the role of… read more here.
Keywords: addiction; role; role circadian; circadian genes ... See more keywords
ARNTL2 is a Prognostic Biomarker and Correlates with Immune Cell Infiltration in Triple-Negative Breast Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s331431
Abstract: Background Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype and is associated with poor prognosis. The aberrant expression of circadian genes contributes to the origin and progression of breast cancer. The present… read more here.
Keywords: circadian genes; cancer; breast cancer; tnbc ... See more keywords
Circadian Genes Expression Patterns in Disorders Due to Enzyme Deficiencies in the Heme Biosynthetic Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10123198
Abstract: Heme is a member of the porphyrins family of cyclic tetrapyrroles and influences various cell processes and signalling pathways. Enzyme deficiencies in the heme biosynthetic pathway provoke rare human inherited metabolic diseases called porphyrias. Protein… read more here.
Keywords: enzyme deficiencies; heme biosynthetic; expression; circadian genes ... See more keywords
Regulation of Circadian Genes Nr1d1 and Nr1d2 in Sex-Different Manners during Liver Aging
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231710032
Abstract: Background: Circadian rhythm is associated with the aging process and sex differences; however, how age and sex can change circadian regulation systems remains unclear. Thus, we aimed to evaluate age- and sex-related changes in gene… read more here.
Keywords: expression; circadian genes; sex; liver aging ... See more keywords
Effects of Dietary Fat to Carbohydrate Ratio on Obesity Risk Depending on Genotypes of Circadian Genes
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14030478
Abstract: Although the impacts of macronutrients and the circadian clock on obesity have been reported, the interactions between macronutrient distribution and circadian genes are unclear. The aim of this study was to explore macronutrient intake patterns… read more here.
Keywords: obesity risk; circadian genes; risk; carbohydrate ratio ... See more keywords
Relationship between circadian genes and memory impairment caused by sleep deprivation
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DOI: 10.7717/peerj.13165
Abstract: Background Sleep deprivation (SD)-induced cognitive impairment is highly prevalent worldwide and has attracted widespread attention. The temporal and spatial oscillations of circadian genes are severely disturbed after SD, leading to a progressive loss of their… read more here.
Keywords: memory function; memory; memory impairment; circadian genes ... See more keywords