Weighted Trigonometric Regression for Suboptimal Designs in Circadian Transcriptome Studies
Sign Up to like & getrecommendations! Published in 2025 at "Statistics in Medicine"
DOI: 10.1002/sim.70201
Abstract: Circadian transcriptome studies often use trigonometric regression to model gene expression over time. Ideally, protocols in these studies would collect tissue samples at evenly distributed and equally spaced time points over a 24‐hour period. This… read more here.
Keywords: circadian transcriptome; transcriptome studies; regression; weighted trigonometric ... See more keywords
Circadian transcriptome of pancreatic adenocarcinoma unravels chronotherapeutic targets
Sign Up to like & getrecommendations! Published in 2024 at "JCI Insight"
DOI: 10.1172/jci.insight.177697
Abstract: Pancreatic ductal adenocarcinoma (PDA) is a lethal cancer characterized by a poor outcome and an increasing incidence. A significant majority (>80%) of newly diagnosed cases are deemed unresectable, leaving chemotherapy as the sole viable option,… read more here.
Keywords: cancer; circadian transcriptome; pda; transcriptome pancreatic ... See more keywords