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   Articles with "circhipk2" as a keyword



CircHIPK2 Contributes Cell Growth in Intestinal Epithelial of Colitis and Colorectal Cancer through Promoting TAZ Translation

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recommendations! Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202401588

Abstract: Colorectal cancer (CRC) and inflammatory bowel disease (IBD) are escalating global health concerns. Despite their distinct clinical presentations, both disorders share intricate genetic and molecular interactions. The Hippo signaling pathway plays a crucial role in… read more here.

Keywords: ibd crc; circhipk2; crc; translation ... See more keywords

Silencing of circular RNA HIPK2 in neural stem cells enhances functional recovery following ischaemic stroke

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recommendations! Published in 2020 at "EBioMedicine"

DOI: 10.1016/j.ebiom.2020.102660

Abstract: Background Circular RNAs (circRNAs) have been reported to be involved in central nervous system (CNS) diseases and to have a close connection with neuronal development. However, the role of circRNAs in neural stem cell (NSC)… read more here.

Keywords: circhipk2 nscs; circhipk2; functional recovery; ischaemic stroke ... See more keywords

circHIPK2 Has a Potentially Important Clinical Significance in Colorectal Cancer Progression via HSP90 Ubiquitination by miR485-5p.

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recommendations! Published in 2022 at "Critical reviews in eukaryotic gene expression"

DOI: 10.1615/critreveukaryotgeneexpr.2022042925

Abstract: Colon cancer, as one of the common malignant tumors, has the highest morbidity and mortality. We investigated the clinical significance and possible mechanism of the circular RNA circHIPK2 in the progression of colorectal cancer (CRC).… read more here.

Keywords: circhipk2; clinical significance; hsp90 ubiquitination; progression ... See more keywords

Sp1-Mediated circRNA circHipk2 Regulates Myogenesis by Targeting Ribosomal Protein Rpl7

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recommendations! Published in 2021 at "Genes"

DOI: 10.3390/genes12050696

Abstract: Circular RNAs (circRNAs) represent a class of covalently closed single-stranded RNA molecules that are emerging as essential regulators of various biological processes. The circRNA circHipk2 originates from exon 2 of the Hipk2 gene in mice… read more here.

Keywords: protein rpl7; circrna circhipk2; circhipk2; ribosomal protein ... See more keywords