Exosome-mediated transfer of circRNA CircNFIX enhances temozolomide resistance in glioma.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.03.002
Abstract: Development of chemotherapy resistance remains a major obstacle for glioma management. Exosome-mediated transfer of circular RNAs (circRNAs) are being found to have relevance to many human cancers, including glioma. The purpose of this study is… read more here.
Keywords: mediated transfer; glioma; circnfix; resistance ... See more keywords
CircNFIX promotes progression of pituitary adenoma via CCNB1 by sponging miR-34a -5p
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2020.111140
Abstract: Previous studies have shown that CCNB1 affects the invasiveness of pituitary adenomas, and it is of great significance to find the upstream mechanism of regulating CCNB1.In this study, we explored a significantly overexpressed circRNA in… read more here.
Keywords: sponging mir; mir 34a; circnfix; pituitary adenomas ... See more keywords
CircNFIX knockdown inhibited AML tumorigenicity by the miR-876-3p/TRIM31 axis
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DOI: 10.1080/16078454.2022.2115699
Abstract: ABSTRACT Background Acute myeloid leukemia (AML) is one of the most common malignant myeloid diseases in adults with a dismal prognosis. We aimed to explore the effects of circNFIX on the proliferation and apoptosis of… read more here.
Keywords: proliferation; mir 876; aml; circnfix knockdown ... See more keywords
Circ_nuclear factor I X (circNfix) attenuates pressure overload-induced cardiac hypertrophy via regulating miR-145-5p/ATF3 axis.
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DOI: 10.1080/21655979.2021.1960462
Abstract: Cardiac hypertrophy can cause heart failure. However, the mechanisms underlying the progression of cardiac hypertrophy remain unclear. Emerging evidence suggests that circular RNAs (circRNAs) play a critical role in cardiac hypertrophy. However, the association between… read more here.
Keywords: cardiac hypertrophy; pressure overload; mir 145; circnfix ... See more keywords