Conformational Dynamics of Nonenveloped Circovirus Capsid to the Host Cell Receptor
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DOI: 10.1016/j.isci.2020.101547
Abstract: Summary Circovirus, comprising one capsid protein, is the smallest nonenveloped virus and induces lymphopenia. Circovirus can be used to explore the cell adhesion mechanism of nonenveloped viruses. We developed a single-molecule fluorescence resonance energy transfer… read more here.
Keywords: conformational dynamics; circovirus; receptor; cell surface ... See more keywords
Porcine circovirus 3 Cap inhibits type I interferon signaling through interaction with STAT2.
Sign Up to like & getrecommendations! Published in 2019 at "Virus research"
DOI: 10.1016/j.virusres.2019.197804
Abstract: Porcine circovirus 3 (PCV3) is a novel circovirus that is associated with porcine dermatitis and nephropathy syndrome, reproductive failure, and multi-systemic inflammation. The type I Interferon (IFN) signaling pathway is an important innate immune signaling… read more here.
Keywords: type interferon; porcine circovirus; circovirus; ifn signaling ... See more keywords
Five years of porcine circovirus 3: what have we learned about the clinical disease, immune pathogenesis, and diagnosis.
Sign Up to like & getrecommendations! Published in 2022 at "Virus research"
DOI: 10.1016/j.virusres.2022.198764
Abstract: Porcine circovirus type 3 (PCV3) is a non-enveloped, circular, single-stranded DNA virus in the family Circoviridae. This member of the genus Circovirus was initially described as affecting swine in 2016, and new research has provided… read more here.
Keywords: response; pathogenesis; infection; clinical disease ... See more keywords
Novel canine circovirus strains from Thailand: Evidence for genetic recombination
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DOI: 10.1038/s41598-018-25936-1
Abstract: Canine circoviruses (CanineCV’s), belonging to the genus Circovirus of the Circoviridae family, were detected by next generation sequencing in samples from Thai dogs with respiratory symptoms. Genetic characterization and phylogenetic analysis of nearly complete CanineCV… read more here.
Keywords: circovirus strains; circovirus; strains thailand; recombination ... See more keywords
Protective efficacy of a DNA vaccine encoding capsid protein of porcine circovirus‐like virus P1 against porcine circovirus 2 in mice
Sign Up to like & getrecommendations! Published in 2018 at "Microbiology and Immunology"
DOI: 10.1111/1348-0421.12571
Abstract: The capsid protein is the major immunogenic protein of porcine circovirus 2 (PCV2). The nucleotide sequence of porcine circovirus‐like virus P1 shares high homology with open reading frame (ORF) 2 of PCV2, and ORF1 of… read more here.
Keywords: capsid protein; protein porcine; porcine circovirus; circovirus ... See more keywords
First detection of porcine circovirus type 3 on commercial pig farms in Poland
Sign Up to like & getrecommendations! Published in 2017 at "Transboundary and Emerging Diseases"
DOI: 10.1111/tbed.12672
Abstract: Porcine circovirus type 3 (PCV3) is a novel circovirus species recently discovered in USA and China in cases of porcine dermatitis and nephropathy syndrome, reproductive failure, respiratory disease and multisystemic inflammation. This study reports on… read more here.
Keywords: first detection; circovirus type; pcv3; porcine circovirus ... See more keywords
Novel circovirus species identified in farmed pigs designated as Porcine circovirus 4, Hunan province, China.
Sign Up to like & getrecommendations! Published in 2019 at "Transboundary and emerging diseases"
DOI: 10.1111/tbed.13446
Abstract: In pigs, three circovirus species within the genus Circovirus have been identified so far, including the non-pathogenic Porcine circovirus 1 (PCV1), the pathogenic Porcine circovirus 2 (PCV2), and the recently identified Porcine circovirus 3 (PCV3).… read more here.
Keywords: province china; hunan province; porcine circovirus; circovirus ... See more keywords
Molecular detection and phylogenetic analysis of Porcine circovirus 4 in Henan and Shanxi Provinces of China.
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DOI: 10.1111/tbed.13714
Abstract: Porcine circovirus 4 (PCV4), a new circovirus with a distinct relationship to other circoviruses, was identified in 2019 in several pigs with severe clinical disease in Hunan Province, China. To investigate the epidemic profile and… read more here.
Keywords: porcine circovirus; circovirus; shanxi provinces; pcv4 ... See more keywords
Porcine circovirus 4 rescued from an infectious clone is replicable and pathogenic in vivo.
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DOI: 10.1111/tbed.14498
Abstract: Porcine circovirus 4 (PCV4) is a newly identified porcine circovirus in pigs, belonging to the Circoviridae family Circovirus genus. The virus was detected in all age groups and aborted fetuses. However, the virus hasn't been… read more here.
Keywords: circovirus; pcv4; rescued infectious; porcine circovirus ... See more keywords
Porcine Circovirus Type 2 Hijacks Host IPO5 to Sustain the Intracytoplasmic Stability of Its Capsid Protein
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01522-22
Abstract: Circovirus is the smallest virus to cause immune suppression in pigs. The capsid protein (Cap) is the only viral structural protein that is closely related to viral infection. ABSTRACT Nuclear entrance and stability of porcine… read more here.
Keywords: capsid protein; replication; circovirus; infection ... See more keywords
First Molecular Detection and Genetic Analysis of a Novel Porcine Circovirus (Porcine Circovirus 4) in Dogs in the World
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DOI: 10.1128/spectrum.04333-22
Abstract: This study is the first to report the presence of PCV4 in dogs worldwide, and the first complete genome sequence was obtained from a dog affected with diarrhea. Three genotypes of PCV4 strains (PCV4a, PCV4b,… read more here.
Keywords: circovirus; pcv4; complete genome; analysis ... See more keywords