Exosomal circPRRX1 functions as a ceRNA for miR-596 to promote the proliferation, migration, invasion, and reduce radiation sensitivity of gastric cancer cells via the upregulation of NF-κB activating protein
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001358
Abstract: Exosomes, which are small extracellular vesicles, have been unveiled to carry circular RNAs (circRNAs). CircRNA paired-related homeobox 1 (circPRRX1) can be transferred by exosomes derived from gastric cancer cells. Here, we investigated the activity and… read more here.
Keywords: radiation sensitivity; mir 596; exosomal circprrx1; gastric cancer ... See more keywords
Exosomal CircPRRX1 Enhances Doxorubicin Resistance in Gastric Cancer by Regulating MiR-3064-5p/PTPN14 Signaling
Sign Up to like & getrecommendations! Published in 2020 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2020.61.9.750
Abstract: Purpose Gastric cancer (GC) is a malignant tumor with a high mortality rate. Drug resistance is a major obstacle to GC therapy. This study aimed to investigate the role and mechanism of exosomal circPRRX1 in… read more here.
Keywords: doxorubicin resistance; 3064 ptpn14; resistance; mir 3064 ... See more keywords