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   Articles with "circpvt1" as a keyword



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Exosomal circPVT1 derived from lung cancer promotes the progression of lung cancer by targeting miR-124-3p/EZH2 axis and regulating macrophage polarization

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recommendations! Published in 2022 at "Cell Cycle"

DOI: 10.1080/15384101.2021.2024997

Abstract: ABSTRACT This study aims to probe the mechanism by which circPVT1 in lung cancer (LC)-derived exosomes (Exos) promotes proliferation, invasion and migration of LC cells by regulating macrophage polarization through miR-124-3p/EZH2 axis. The expressions of… read more here.

Keywords: circpvt1; lung cancer; macrophage polarization; mir 124 ... See more keywords
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circPVT1 promotes osteosarcoma glycolysis and metastasis by sponging miR‐423‐5p to activate Wnt5a/Ror2 signaling

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recommendations! Published in 2020 at "Cancer Science"

DOI: 10.1111/cas.14787

Abstract: Osteosarcoma (OS) is the most prevalent form of bone cancer. It has a high metastatic potential and progresses rapidly. The molecular mechanisms of OS remain unclear and this study aims to examine the functional role… read more here.

Keywords: circpvt1; mir 423; wnt5a ror2; glycolysis ... See more keywords
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Circular RNA PVT1 expression and its roles in acute lymphoblastic leukemia.

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recommendations! Published in 2018 at "Epigenomics"

DOI: 10.2217/epi-2017-0142

Abstract: AIM The roles of circular RNA PVT1 (circPVT1) are explored in the patients with acute lymphoblastic leukemia (ALL). METHODS The circPVT1 level was detected by qRT-PCR and western blot. The apoptotic cells were examined by… read more here.

Keywords: circular rna; lymphoblastic leukemia; rna pvt1; expression ... See more keywords

Circular RNA CircPVT1 Inhibits 5-Fluorouracil Chemosensitivity by Regulating Ferroptosis Through MiR-30a-5p/FZD3 Axis in Esophageal Cancer Cells

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recommendations! Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.780938

Abstract: Background CircPVT1 is demonstrated to promote cancer progression in esophageal squamous cell carcinoma (ESCC). However, the role and potential functional mechanisms of circPVT1 in regulating 5-fluorouracil (5-FU) chemosensitivity remain largely unknown. Methods ESCC cells resistant… read more here.

Keywords: ferroptosis; fzd3; chemosensitivity; circpvt1 ... See more keywords