CircRNA expression profile of bovine placentas in late gestation with aberrant SCNT fetus
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22918
Abstract: One of the limitations of somatic cell nuclear transfer (SCNT) strategy to generate genetically modified offspring is the low birth rate. Placental dysfunction is one of the causes of abortion. Circular RNA (circRNA) is noncoding… read more here.
Keywords: expression profile; profile bovine; bovine placentas; circrna ... See more keywords
Circular RNA expression profile of articular chondrocytes in an IL-1β-induced mouse model of osteoarthritis.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2017.12.020
Abstract: Osteoarthritis (OA) is a widely prevalent degenerative joint disease characterized by articular cartilage degradation and joint inflammation. The pathogenesis of OA remains unclear, leading to a lack of effective treatment. Previous studies have reported that… read more here.
Keywords: osteoarthritis; model; articular chondrocytes; expression ... See more keywords
CircRNA_0079586 and circRNA_RanGAP1 are involved in the pathogenesis of intracranial aneurysms rupture by regulating the expression of MPO
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-99062-w
Abstract: Several circRNAs have been reported to be dysregulated in human endothelial cells through sponging miRNAs. Previous reports demonstrated that MPO not only contributed to the formation and rupture of cerebral aneurysm but was also correlated… read more here.
Keywords: 0079586 circrna; circrna; expression; circrna 0079586 ... See more keywords
High-throughput analysis of CircRNA in cows with naturally infected Staphylococcus aureus mammary gland.
Sign Up to like & getrecommendations! Published in 2022 at "Animal biotechnology"
DOI: 10.1080/10495398.2022.2140056
Abstract: Circular RNAs (CircRNA) are a special type of non-coding RNA molecule with a closed ring structure and are not affected by RNA exonucases. It has stable expression, is not easy to degrade, and exists in… read more here.
Keywords: circrna; expressed circrnas; mastitis; differentially expressed ... See more keywords
Analysis of pig transcriptomes suggests a global regulation mechanism enabling temporary bursts of circular RNAs
Sign Up to like & getrecommendations! Published in 2019 at "RNA Biology"
DOI: 10.1080/15476286.2019.1621621
Abstract: ABSTRACT To investigate the dynamics of circRNA expression in pig testes, we designed specific strategies to individually study circRNA production from intron lariats and circRNAs originating from back-splicing of two exons. By applying these methods… read more here.
Keywords: production; rna; circrna; rna seq ... See more keywords
Hsa_circ_0000081 promotes the function of gastric cancer through sponging hsa-miR-423-5p to influence 3-phosphoinositide-dependent kinase 1 expression
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2053796
Abstract: ABSTRACT Gastric cancer (GC) is one of the most common malignancies in the world, and effective therapeutic targets need to be identified for this type of cancer. In this study, circular RNA (circRNA) microarray analysis… read more here.
Keywords: circrna; circ 0000081; expression; hsa circ ... See more keywords
Sensitive, reliable and robust circRNA detection from RNA-seq with CirComPara2.
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbab418
Abstract: Circular RNAs (circRNAs) are a large class of covalently closed RNA molecules originating by a process called back-splicing. CircRNAs are emerging as functional RNAs involved in the regulation of biological processes as well as in… read more here.
Keywords: rna; circrna; circrna detection; rna seq ... See more keywords
Collaborative deep learning improves disease-related circRNA prediction based on multi-source functional information
Sign Up to like & getrecommendations! Published in 2023 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbad069
Abstract: Emerging studies have shown that circular RNAs (circRNAs) are involved in a variety of biological processes and play a key role in disease diagnosing, treating and inferring. Although many methods, including traditional machine learning and… read more here.
Keywords: information; circrna; disease related; multi ... See more keywords
Microarray is an efficient tool for circRNA profiling
Sign Up to like & getrecommendations! Published in 2019 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bby006
Abstract: Circular RNAs (circRNAs) are emerging as a new class of endogenous and regulatory noncoding RNAs in latest years. With the widespread application of RNA sequencing (RNA-seq) technology and bioinformatics prediction, large numbers of circRNAs have… read more here.
Keywords: rna seq; circrna; circrna profiling; microarray efficient ... See more keywords
Closing the circle: current state and perspectives of circular RNA databases
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbz175
Abstract: Abstract Circular RNAs (circRNAs) are covalently closed RNA molecules that have been linked to various diseases, including cancer. However, a precise function and working mechanism are lacking for the larger majority. Following many different experimental… read more here.
Keywords: circrna databases; rna; closing circle; current state ... See more keywords
Comprehensive comparison of two types of algorithm for circRNA detection from short-read RNA-Seq
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac302
Abstract: MOTIVATION Circular RNA is generally formed by the "back-splicing" process between the upstream splice acceptor and the downstream donor in/not in the regulation of the corresponding RNA-binding proteins or cis-elements. Therefore, more and more software… read more here.
Keywords: circrna; types algorithm; rna seq; two types ... See more keywords