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   Articles with "circrna" as a keyword



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CircRNA expression profile of bovine placentas in late gestation with aberrant SCNT fetus

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recommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.22918

Abstract: One of the limitations of somatic cell nuclear transfer (SCNT) strategy to generate genetically modified offspring is the low birth rate. Placental dysfunction is one of the causes of abortion. Circular RNA (circRNA) is noncoding… read more here.

Keywords: expression profile; profile bovine; bovine placentas; circrna ... See more keywords

Placental Alterations in Autism Spectrum Disorder: An In Silico Approach to circRNA–miRNA–mRNA Networks

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recommendations! Published in 2025 at "International Journal of Developmental Neuroscience"

DOI: 10.1002/jdn.70064

Abstract: ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by deficits in social communication and repetitive behaviours with an aetiology involving genetic and environmental risk factors. Placental alterations, such as epigenetic DNA methylation and… read more here.

Keywords: placental alterations; spectrum disorder; circrna mirna; autism spectrum ... See more keywords

Circular RNA expression profile of articular chondrocytes in an IL-1β-induced mouse model of osteoarthritis.

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recommendations! Published in 2018 at "Gene"

DOI: 10.1016/j.gene.2017.12.020

Abstract: Osteoarthritis (OA) is a widely prevalent degenerative joint disease characterized by articular cartilage degradation and joint inflammation. The pathogenesis of OA remains unclear, leading to a lack of effective treatment. Previous studies have reported that… read more here.

Keywords: osteoarthritis; model; articular chondrocytes; expression ... See more keywords

CircRNA_0079586 and circRNA_RanGAP1 are involved in the pathogenesis of intracranial aneurysms rupture by regulating the expression of MPO

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recommendations! Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-99062-w

Abstract: Several circRNAs have been reported to be dysregulated in human endothelial cells through sponging miRNAs. Previous reports demonstrated that MPO not only contributed to the formation and rupture of cerebral aneurysm but was also correlated… read more here.

Keywords: 0079586 circrna; circrna; expression; circrna 0079586 ... See more keywords

Construction of ceRNA networks in joint tissues of gouty arthritis rats based on transcriptome sequencing

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recommendations! Published in 2025 at "AIP Advances"

DOI: 10.1063/5.0271292

Abstract: The aim of this study is to construct a competitive endogenous RNA regulatory network of gouty arthritis through transcriptomics and investigate its underlying pathogenesis. Transcriptomics was performed with the rats’ joints in both the control… read more here.

Keywords: gouty arthritis; circrna mirna; lncrna circrna; circrna ... See more keywords

High-throughput analysis of CircRNA in cows with naturally infected Staphylococcus aureus mammary gland.

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recommendations! Published in 2022 at "Animal biotechnology"

DOI: 10.1080/10495398.2022.2140056

Abstract: Circular RNAs (CircRNA) are a special type of non-coding RNA molecule with a closed ring structure and are not affected by RNA exonucases. It has stable expression, is not easy to degrade, and exists in… read more here.

Keywords: circrna; expressed circrnas; mastitis; differentially expressed ... See more keywords

Analysis of pig transcriptomes suggests a global regulation mechanism enabling temporary bursts of circular RNAs

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recommendations! Published in 2019 at "RNA Biology"

DOI: 10.1080/15476286.2019.1621621

Abstract: ABSTRACT To investigate the dynamics of circRNA expression in pig testes, we designed specific strategies to individually study circRNA production from intron lariats and circRNAs originating from back-splicing of two exons. By applying these methods… read more here.

Keywords: production; rna; circrna; rna seq ... See more keywords

Hsa_circ_0000081 promotes the function of gastric cancer through sponging hsa-miR-423-5p to influence 3-phosphoinositide-dependent kinase 1 expression

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2053796

Abstract: ABSTRACT Gastric cancer (GC) is one of the most common malignancies in the world, and effective therapeutic targets need to be identified for this type of cancer. In this study, circular RNA (circRNA) microarray analysis… read more here.

Keywords: circrna; circ 0000081; expression; hsa circ ... See more keywords

Sensitive, reliable and robust circRNA detection from RNA-seq with CirComPara2.

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recommendations! Published in 2021 at "Briefings in bioinformatics"

DOI: 10.1093/bib/bbab418

Abstract: Circular RNAs (circRNAs) are a large class of covalently closed RNA molecules originating by a process called back-splicing. CircRNAs are emerging as functional RNAs involved in the regulation of biological processes as well as in… read more here.

Keywords: rna; circrna; circrna detection; rna seq ... See more keywords

Collaborative deep learning improves disease-related circRNA prediction based on multi-source functional information

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recommendations! Published in 2023 at "Briefings in bioinformatics"

DOI: 10.1093/bib/bbad069

Abstract: Emerging studies have shown that circular RNAs (circRNAs) are involved in a variety of biological processes and play a key role in disease diagnosing, treating and inferring. Although many methods, including traditional machine learning and… read more here.

Keywords: information; circrna; disease related; multi ... See more keywords

Microarray is an efficient tool for circRNA profiling

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recommendations! Published in 2019 at "Briefings in bioinformatics"

DOI: 10.1093/bib/bby006

Abstract: Circular RNAs (circRNAs) are emerging as a new class of endogenous and regulatory noncoding RNAs in latest years. With the widespread application of RNA sequencing (RNA-seq) technology and bioinformatics prediction, large numbers of circRNAs have… read more here.

Keywords: rna seq; circrna; circrna profiling; microarray efficient ... See more keywords