Identification and analysis of circRNAs in the prefrontal cortices of wild boar and domestic pig.
Sign Up to like & getrecommendations! Published in 2022 at "Animal biotechnology"
DOI: 10.1080/10495398.2022.2109040
Abstract: Domestication caused significant differences in morphology and behavior between wild and domestic pigs. However, the regulatory role of circRNA in this event is unclear. Here, we analyzed circRNA expression patterns in the prefrontal cortices of… read more here.
Keywords: pig; cortices wild; ssc; prefrontal cortices ... See more keywords
CircRnas in atherosclerosis, with special emphasis on the spongy effect of circRnas on miRnas
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2133365
Abstract: ABSTRACT Atherosclerosis (AS) is a chronic inflammatory disease, which leads to atherosclerotic rupture, lumen stenosis and thrombosis, and often endangers life. Circular RNAs (circRNAs) are a special class of non-coding RNA molecules, whose abnormal expression… read more here.
Keywords: circrnas atherosclerosis; effect; atherosclerosis special; atherosclerosis ... See more keywords
TRCirc: a resource for transcriptional regulation information of circRNAs
Sign Up to like & getrecommendations! Published in 2019 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bby083
Abstract: In recent years, high-throughput genomic technologies like chromatin immunoprecipitation sequencing (ChIp-seq) and transcriptome sequencing (RNA-seq) have been becoming both more refined and less expensive, making them more accessible. Many circular RNAs (circRNAs) that originate from… read more here.
Keywords: trcirc; circrnas; information circrnas; regulation ... See more keywords
Inhibition of SARS-CoV-2 coronavirus proliferation by designer antisense-circRNAs
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab1096
Abstract: Abstract Circular RNAs (circRNAs) are noncoding RNAs that exist in all eukaryotes investigated and are derived from back-splicing of certain pre-mRNA exons. Here, we report the application of artificial circRNAs designed to act as antisense-RNAs.… read more here.
Keywords: sars cov; proliferation; antisense circrnas; circrnas ... See more keywords
Crosstalk between circRNAs and the PI3K/AKT and/or MEK/ERK signaling pathways in digestive tract malignancy progression.
Sign Up to like & getrecommendations! Published in 2023 at "Future oncology"
DOI: 10.2217/fon-2022-0429
Abstract: Evidence indicates that circular RNAs (circRNAs) may play an important role in regulating gene expression by binding to miRNAs through miRNA response elements. circRNAs are formed by back-splicing and have a covalently closed structure. The… read more here.
Keywords: erk signaling; pi3k akt; circrnas; mek erk ... See more keywords
Editorial: Emerging Roles of Circular RNAs in the Tumor: Functions and Potential Applications
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.846926
Abstract: Circular RNA (circRNA), which was firstly described in mammals in 1991, has undergone an explosion in studies on its biology resulting in the common understanding of the molecule’s role as important players in physiology and… read more here.
Keywords: cell; cancer; tumor; biology ... See more keywords
Exploratory Circular RNA Profiling in Adrenocortical Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14174313
Abstract: Simple Summary The histological differential diagnosis of adrenocortical adenoma and carcinoma is difficult and requires great expertise. Measures taken towards the distinction of adrenal tumors are of paramount importance. The non-coding circular RNAs (circRNAs) were… read more here.
Keywords: profiling adrenocortical; adrenocortical tumors; aca; next generation ... See more keywords
Identification and Functional Prediction of CircRNAs in Leaves of F1 Hybrid Poplars with Different Growth Potential and Their Parents
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032284
Abstract: Circular RNAs (CircRNAs) regulate plant growth and development; however, their role in poplar heterosis is unclear. We identified 3722 circRNAs in poplar leaves, most of which were intergenic (57.2%) and exonic (40.2%). The expression of… read more here.
Keywords: poplar heterosis; growth; expression; growth potential ... See more keywords
Multiplex Analysis of CircRNAs from Plasma Extracellular Vesicle-Enriched Samples for the Detection of Early-Stage Non-Small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14102034
Abstract: Background: The analysis of liquid biopsies brings new opportunities in the precision oncology field. Under this context, extracellular vesicle circular RNAs (EV-circRNAs) have gained interest as biomarkers for lung cancer (LC) detection. However, standardized and… read more here.
Keywords: lung cancer; early stage; analysis circrnas; extracellular vesicle ... See more keywords
RNAseq profiling of circRNA expression in radiation-treated A549 cells and bioinformatics analysis of radiation-related circRNA-miRNA networks
Sign Up to like & getrecommendations! Published in 2020 at "Oncology Letters"
DOI: 10.3892/ol.2020.11698
Abstract: With the development of new biochemical and computational methods, circular RNAs (circRNAs) have been identified as microRNA sponges. circRNAs are associated with many diseases, particularly cancer. The present study aimed to investigate the expression profile… read more here.
Keywords: a549 cells; analysis; treated a549; circrnas ... See more keywords