Decreases in the number of microglia and neural circuit dysfunction elicited by developmental exposure to neonicotinoid pesticides in mice
Sign Up to like & getrecommendations! Published in 2024 at "Environmental Toxicology"
DOI: 10.1002/tox.24263
Abstract: Neonicotinoids are insecticides widely used in the world. Although neonicotinoids are believed to be toxic only to insects, their developmental neurotoxicity in mammals is a concern. Therefore, we examined the effects of developmental exposure to… read more here.
Keywords: number; neural circuit; circuit dysfunction; developmental exposure ... See more keywords
Mechanisms Underlying Circuit Dysfunction in Neurodevelopmental Disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of genetics"
DOI: 10.1146/annurev-genet-072820-023642
Abstract: Recent advances in genomics have revealed a wide spectrum of genetic variants associated with neurodevelopmental disorders at an unprecedented scale. An increasing number of studies have consistently identified mutations-both inherited and de novo-impacting the function… read more here.
Keywords: neurodevelopmental disorders; circuit; underlying circuit; mechanisms underlying ... See more keywords
Cortical Circuit Dysfunction as a Potential Driver of Amyotrophic Lateral Sclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2020.00363
Abstract: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects selected cortical and spinal neuronal populations, leading to progressive paralysis and death. A growing body of evidences suggests that the disease may originate in… read more here.
Keywords: circuit dysfunction; amyotrophic lateral; cortical circuit; lateral sclerosis ... See more keywords