Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202503966
Abstract: Due to an inhibitory scar microenvironment that prevents neural circuit reconstruction, spinal cord injury (SCI) often leads to persistent neurological dysfunction. Although neonatal murine models demonstrate that microglial inhibition enables scar remodeling to support neuroregeneration… read more here.
Keywords: circuit; circuit reconstruction; spinal cord; sci ... See more keywords
Dense Circuit Reconstruction to Understand Neuronal Computation: Focus on Zebrafish.
Sign Up to like & getrecommendations! Published in 2021 at "Annual review of neuroscience"
DOI: 10.1146/annurev-neuro-110220-013050
Abstract: The dense reconstruction of neuronal wiring diagrams from volumetric electron microscopy data has the potential to generate fundamentally new insights into mechanisms of information processing and storage in neuronal circuits. Zebrafish provide unique opportunities for… read more here.
Keywords: reconstruction; wiring diagrams; connectomics; circuit ... See more keywords