Association of Brain Reward Response With Body Mass Index and Ventral Striatal-Hypothalamic Circuitry Among Young Women With Eating Disorders
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2021.1580
Abstract: Key Points Question Is brain reward response associated with specific behaviors across the eating disorder diagnostic spectrum? Findings In this cross-sectional functional brain imaging study of 197 women with anorexia nervosa, other specified feeding and… read more here.
Keywords: brain; brain reward; circuitry; reward response ... See more keywords
Dopamine elevates and lowers astroglial Ca2+ through distinct pathways depending on local synaptic circuitry
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23103
Abstract: Whilst astrocytes in culture invariably respond to dopamine with cytosolic Ca2+ rises, the dopamine sensitivity of astroglia in situ and its physiological roles remain unknown. To minimize effects of experimental manipulations on astroglial physiology, here… read more here.
Keywords: dopamine elevates; elevates lowers; dopamine; ca2 ... See more keywords
Threat vigilance and intrinsic amygdala connectivity.
Sign Up to like & getrecommendations! Published in 2022 at "Human brain mapping"
DOI: 10.1002/hbm.25851
Abstract: A well-documented amygdala-dorsomedial prefrontal circuit is theorized to promote attention to threat ("threat vigilance"). Prior research has implicated a relationship between individual differences in trait anxiety/vigilance, engagement of this circuitry, and anxiogenic features of the… read more here.
Keywords: threat; connectivity; circuitry; threat vigilance ... See more keywords
The structure of hippocampal circuitry relates to rapid category learning in humans
Sign Up to like & getrecommendations! Published in 2021 at "Hippocampus"
DOI: 10.1002/hipo.23382
Abstract: Prior work suggests that complementary white matter pathways within the hippocampus (HPC) differentially support the learning of specific versus general information. In particular, while the trisynaptic pathway (TSP) rapidly forms memories for specific experiences, the… read more here.
Keywords: learning humans; category learning; structure; circuitry ... See more keywords
Anhedonia in Posttraumatic Stress Disorder: Prevalence, Phenotypes, and Neural Circuitry.
Sign Up to like & getrecommendations! Published in 2021 at "Current topics in behavioral neurosciences"
DOI: 10.1007/7854_2021_292
Abstract: Anhedonia, the reduction of pleasure and reward-seeking behavior, is a transdiagnostic construct associated with a range of important health outcomes. As with other psychiatric disorders, anhedonia is a relatively common, though understudied, feature of posttraumatic… read more here.
Keywords: anhedonia; disorder; circuitry; posttraumatic stress ... See more keywords
Absence of Mutation Enrichment for Genes Phylogenetically Conserved in the Olivocerebellar Motor Circuitry in a Cohort of Canadian Essential Tremor Cases
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1369-1
Abstract: Essential Tremor is a prevalent neurological disorder of unknown etiology. Studies suggest that genetic factors contribute to this pathology. To date, no causative mutations in a gene have been reproducibly reported. All three structures of… read more here.
Keywords: olivocerebellar motor; cohort canadian; tremor; circuitry ... See more keywords
Dynamically Timed Stimulation of Corticolimbic Circuitry Activates a Stress-Compensatory Pathway
Sign Up to like & getrecommendations! Published in 2017 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2017.06.008
Abstract: BACKGROUND The prefrontal cortex plays a critical role in regulating emotional behaviors, and dysfunction of prefrontal cortex-dependent networks has been broadly implicated in mediating stress-induced behavioral disorders including major depressive disorder. METHODS Here we acquired… read more here.
Keywords: dynamically timed; compensatory; stimulation; stress ... See more keywords
SU72 TRANSCRIPTOME STUDY IN OBSESSIVE COMPULSIVE DISORDERS
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.261
Abstract: Background Obsessive Compulsive Disorder (OCD) is a psychiatric disorder characterized by obsessions and compulsions. The features of OCD are intrusive thoughts (obsessions) and repetitive behavior (compulsions). Functional neuroimaging studies indicate that OCD is a heterogeneous… read more here.
Keywords: obsessive compulsive; ventral cognitive; exclusive degs; gene ... See more keywords
Abnormalities within and beyond the cortico-striato-thalamo-cortical circuitry in medication-free patients with OCD revealed by the fractional amplitude of low-frequency fluctuations and resting-state functional connectivity
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.134449
Abstract: Neuroimaging studies of obsessive-compulsive disorder (OCD) often focus on the cortico-striato-thalamo-cortical (CSTC) circuitry, but recent studies have found abnormal spontaneous brain activity in regions outside the CSTC circuitry in patients with OCD using resting-state functional… read more here.
Keywords: patients ocd; resting state; state functional; circuitry ... See more keywords
Basolateral amygdala – nucleus accumbens circuitry regulates optimal cue-guided risk/reward decision making
Sign Up to like & getrecommendations! Published in 2020 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2019.109830
Abstract: Maladaptive decision making is a characteristic feature of substance use disorder and pathological gambling. Studies in humans and animals have implicated neural circuits that include the basolateral amygdala (BLA) and nucleus accumbens (NAc) in facilitating… read more here.
Keywords: decision; risk reward; reward decision; decision making ... See more keywords
Neural circuitry and precision medicines for mental disorders: are they compatible?
Sign Up to like & getrecommendations! Published in 2018 at "Psychological Medicine"
DOI: 10.1017/s0033291718003252
Abstract: Abstract Given the failure of psychiatry to develop clinically useful biomarkers for psychiatric disorders, and the concomitant failure to develop significant advances in diagnosis and treatment, the National Institute of Mental Health (NIMH) in 2010… read more here.
Keywords: medicine; circuitry; neural circuitry; mental disorders ... See more keywords