A PK/PD Analysis of Circulating Biomarkers and Their Relationship to Tumor Response in Atezolizumab‐Treated non‐small Cell Lung Cancer Patients
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.1198
Abstract: To assess circulating biomarkers as predictors of antitumor response to atezolizumab (anti‐programmed death‐ligand 1 (PD‐L1), Tecentriq) serum pharmacokinetic (PK) and 95 plasma biomarkers were analyzed in 88 patients with relapsed/refractory non‐small cell lung cancer (NSCLC)… read more here.
Keywords: circulating biomarkers; response; response atezolizumab; non small ... See more keywords
Integration of imaging and circulating biomarkers in heart failure: a Consensus Document by the Biomarkers and Imaging Study Groups of the Heart Failure Association of the ESC.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of heart failure"
DOI: 10.1002/ejhf.2339
Abstract: Circulating biomarkers and imaging techniques provide independent and complementary information to guide management of heart failure (HF). This consensus document by the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) presents current… read more here.
Keywords: heart; circulating biomarkers; heart failure; document ... See more keywords
Using circulating biomarkers to stage hepatocellular carcinoma: Pitfalls and limitations.
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31618
Abstract: We read with interest the paper "HepatoScore-14: Measures of biological heterogeneity significantly improve prediction of hepatocellular carcinoma risk" by Dr. Morris et al. published in an upcoming issue of Hepatology.1 It is an elegant study… read more here.
Keywords: hepatocellular carcinoma; circulating biomarkers; biomarkers stage; using circulating ... See more keywords
Fatty acid amides as potential circulating biomarkers for sarcopenia
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13244
Abstract: Sarcopenia is characterized by a progressive decrease in skeletal muscle mass and function with age. Given that sarcopenia is associated with various metabolic disorders, effective metabolic biomarkers for its early detection are required. We aimed… read more here.
Keywords: amides potential; potential circulating; acid amides; circulating biomarkers ... See more keywords
Circulating Biomarkers in Heart Failure.
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DOI: 10.1007/5584_2017_140
Abstract: Biological markers have served for diagnosis, risk stratification and guided therapy of heart failure (HF). Our knowledge regarding abilities of biomarkers to relate to several pathways of HF pathogenesis and reflect clinical worsening or improvement… read more here.
Keywords: biomarkers heart; heart; circulating biomarkers; risk stratification ... See more keywords
Fucosylation genes as circulating biomarkers for lung cancer
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DOI: 10.1007/s00432-018-2735-0
Abstract: PurposeFucosyltransferases (FUTs) catalyze fucosylation, which plays a central role in biological processes. Aberrant fucosylation is associated with malignant transformation. Here we investigated whether transcriptional levels of genes coding the FUTs in plasma could provide cell-free… read more here.
Keywords: circulating biomarkers; fucosylation; biomarkers lung; lung cancer ... See more keywords
Circulating biomarkers of inflammaging as potential predictors of COVID-19 severe outcomes
Sign Up to like & getrecommendations! Published in 2022 at "Mechanisms of Ageing and Development"
DOI: 10.1016/j.mad.2022.111667
Abstract: The COVID-19 pandemic caused by SARS-CoV-2 infection has been of unprecedented clinical and socio-economic worldwide relevance. The case fatality rate for COVID-19 grows exponentially with age and the presence of comorbidities. In elderly patients, COVID-19… read more here.
Keywords: potential predictors; biomarkers inflammaging; inflammaging potential; severe outcomes ... See more keywords
Circulating biomarkers of response to immunotherapy and immune-related adverse events
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2022.2130688
Abstract: ABSTRACT Introduction Immune checkpoint blockade has revolutionized cancer treatment. However, response rates vary, and these treatments have a high rate of immune-related side effects, which can be limiting. Thus, tests to predict who will respond… read more here.
Keywords: oncology; immune related; related adverse; circulating biomarkers ... See more keywords
Clustering ICU patients with sepsis based on the patterns of their circulating biomarkers: A secondary analysis of the CAPTAIN prospective multicenter cohort study
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1101/2022.04.12.22273767
Abstract: Background Although sepsis is a life-threatening condition, its heterogeneous presentation likely explains the negative results of most trials on adjunctive therapy. This study in patients with sepsis aimed to identify subgroups with similar immune profiles… read more here.
Keywords: sepsis; secondary analysis; patients sepsis; circulating biomarkers ... See more keywords
Exosomal miRNAs as circulating biomarkers for prediction of development of haematogenous metastasis after surgery for stage II/III gastric cancer
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15253
Abstract: Exosomes secreted by living cancer cells can regulate metastasis. Exosomal miRNAs can reflect pathological conditions of the original cancer cells. Therefore, we aim to identify exosomal miRNAs as circulating biomarkers for haematogenous metastasis of gastric… read more here.
Keywords: exosomal mirnas; circulating biomarkers; haematogenous metastasis; gastric cancer ... See more keywords
Biomarkers of adverse drug reactions
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DOI: 10.1177/1535370217733425
Abstract: Adverse drug reactions can be caused by a wide range of therapeutics. Adverse drug reactions affect many bodily organ systems and vary widely in severity. Milder adverse drug reactions often resolve quickly following withdrawal of… read more here.
Keywords: biomarkers potential; circulating biomarkers; drug reactions; drug ... See more keywords