Identification and validation of circulating exosomes‐based liquid biopsy for esophageal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2224
Abstract: Early detection of esophageal squamous cell carcinoma (ESCC) recurrence is a key element for follow‐up care and surveillance. The aim of this study is to detect the level of circulating exosomes (CEs) in ESCC patient… read more here.
Keywords: identification validation; circulating exosomes; exosomes based; based liquid ... See more keywords
A Preliminary Proteomic Investigation of Circulating Exosomes and Discovery of Biomarkers Associated with the Progression of Osteosarcoma in a Clinical Model of Spontaneous Disease1
Sign Up to like & getrecommendations! Published in 2018 at "Translational Oncology"
DOI: 10.1016/j.tranon.2018.07.004
Abstract: Circulating cancer exosomes are microvesicles which originate from malignant cells and other organs influenced by the disease and can be found in blood. The exosomal proteomic cargo can often be traced to the cells from… read more here.
Keywords: proteomic investigation; investigation circulating; discovery biomarkers; circulating exosomes ... See more keywords
Characterization of the Angiogenic and Proteomic Features of Circulating Exosomes in a Canine Mandibular Model of Distraction Osteogenesis.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.4c00365
Abstract: Distraction osteogenesis (DO) represents a highly effective method for addressing significant bone defects; however, it necessitates a long treatment period. Exosomes are key mediators of intercellular communication. To investigate their role in the angiogenesis and… read more here.
Keywords: osteogenesis; canine mandibular; circulating exosomes; distraction osteogenesis ... See more keywords
Circulating exosomes and exosomal microRNAs as biomarkers in gastrointestinal cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Gene Therapy"
DOI: 10.1038/cgt.2016.77
Abstract: The most important biological function of exosomes is their possible use as biomarkers in clinical diagnosis. Compared with biomarkers identified in conventional specimens such as serum or urine, exosomal biomarkers provide the highest amount of… read more here.
Keywords: exosomal micrornas; exosomal mirnas; circulating exosomes; biomarkers gastrointestinal ... See more keywords
Impact of sepsis on circulating exosomes: pathophysiological mechanisms, biomarker potential, and therapeutic applications.
Sign Up to like & getrecommendations! Published in 2025 at "International journal of surgery"
DOI: 10.1097/js9.0000000000003129
Abstract: This comprehensive review examines the complex interplay between sepsis and circulating exosomes. Sepsis, characterized by dysregulated host response to infection leading to life-threatening organ dysfunction, remains a significant global health challenge with high mortality rates.… read more here.
Keywords: impact sepsis; sepsis circulating; pathophysiological mechanisms; circulating exosomes ... See more keywords
Circulating exosomes in sepsis induce PD-1 expression in macrophages and promote Th17 differentiation.
Sign Up to like & getrecommendations! Published in 2025 at "International journal of surgery"
DOI: 10.1097/js9.0000000000003651
Abstract: BACKGROUND Sepsis induces complex immunological responses; however, the role of circulating exosomes in regulating macrophage function and T cell responses remains unknown. This study examined the effects of sepsis-derived exosomes on macrophages and their subsequent… read more here.
Keywords: differentiation; clp exo; culture; circulating exosomes ... See more keywords
PD‐L1 in circulating exosomes of Merkel cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Dermatology"
DOI: 10.1111/exd.14520
Abstract: Exosomes, as potential circulated biomarkers, have recently become a topic of interest in the field of oncology. Immune checkpoint molecule PD‐L1 has recently been detected in circulating exosomes from cancer patients. The purpose of this… read more here.
Keywords: cell carcinoma; merkel cell; mcc patients; exosomes mcc ... See more keywords
Diagnostic value of dysregulated microribonucleic acids in the placenta and circulating exosomes in gestational diabetes mellitus
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Diabetes Investigation"
DOI: 10.1111/jdi.13493
Abstract: Differentially expressed microribonucleic acids (miRNAs) in the placenta and circulating exosomes are of diagnostic value for gestational diabetes mellitus (GDM). In a cross‐sectional study, we identified miRNAs expressed both in the placenta and circulating exosomes… read more here.
Keywords: gestational diabetes; microribonucleic acids; placenta circulating; circulating exosomes ... See more keywords
Abstract 2990: Differential micro-RNA expression in circulating exosomes of pancreatic ductal adenocarcinoma patients
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-2990
Abstract: Pancreatic ductal Adenocarcinoma (PDAC) is a highly lethal solid tumor with 5-year survival rate of 5-8%. Extracellular vesicles like exosomes circulating in the blood are crucial mediators of intracellular communication, immunomodulation and tumor progression. The… read more here.
Keywords: ductal adenocarcinoma; circulating exosomes; expression; adenocarcinoma patients ... See more keywords
Circulating exosomes and their cargos in blood as novel biomarkers for cancer
Sign Up to like & getrecommendations! Published in 2018 at "Translational cancer research"
DOI: 10.21037/16197
Abstract: Exosomes, the bilayer-lipid-membrane microvesicles are well known for intercellular communications. They are considered to be involved in tumorigenesis, progression and chemotherapy resistance via horizontal transfer of their functional biomolecules (i.e., proteins and nucleic acids) to… read more here.
Keywords: blood novel; circulating exosomes; cargos blood; exosomes cargos ... See more keywords
Circulating Exosomes as Potential Biomarkers in Cardiovascular Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Current pharmaceutical design"
DOI: 10.2174/1381612825666181219162655
Abstract: Cardiovascular disease (CVD) is the first leading cause of morbidity and mortality in developing and developed countries. Circulating exosomes have recently been identified as extracellular transporters, detectable in biological fluids. Exosomes have established a new… read more here.
Keywords: exosomes potential; biomarkers cardiovascular; circulating exosomes; potential biomarkers ... See more keywords