The Number of Circulating Fetal Extravillous Trophoblasts Varies from Gestational Week 6 to 20
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive Sciences"
DOI: 10.1007/s43032-020-00243-1
Abstract: Cell-based non-invasive prenatal testing (cbNIPT) based on circulating fetal extravillous trophoblasts (fEVTs) has shown to be possible in gestational week (GW) 10–13. Prenatal testing is relevant for a wider time period than GW 10–13, but… read more here.
Keywords: extravillous trophoblasts; number circulating; fetal extravillous; number ... See more keywords
A Reappraisal of Circulating Fetal Cell Noninvasive Prenatal Testing.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2018.11.001
Abstract: New tools for higher-resolution fetal genome analysis including microarray and next-generation sequencing have revolutionized prenatal screening. This article provides commentary on this rapidly advancing field and a future perspective emphasizing circulating fetal cell (CFC) utility.… read more here.
Keywords: prenatal testing; fetal cell; circulating fetal; noninvasive prenatal ... See more keywords
Stimuli-Responsive Microfluidic Interface Enables Highly Efficient Capture and Release of Circulating Fetal Cells for Non-Invasive Prenatal Testing.
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DOI: 10.1021/acs.analchem.0c01622
Abstract: Circulating fetal nucleated cells (CFCs) carrying whole genomic coding of the fetus in maternal blood have been pursued as ideal biomarkers for non-invasive prenatal testing (NIPT). However, a significant limitation is the need to enrich… read more here.
Keywords: invasive prenatal; prenatal testing; non invasive; stimuli responsive ... See more keywords
Aptamer-Mediated Enrichment of Rare Circulating Fetal Nucleated Red Blood Cells for Noninvasive Prenatal Diagnosis.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c00115
Abstract: Isolation of circulating fetal nucleated red blood cells (cfNRBCs) from maternal peripheral blood provides a superior strategy for noninvasive prenatal genetic diagnosis. Recent technical advances in single-cell isolation and genetic analyses have promoted the clinical… read more here.
Keywords: noninvasive prenatal; blood; circulating fetal; prenatal diagnosis ... See more keywords