The pathophysiological and clinical relevance of combined measurement of natriuretic peptides and cardiac troponins for risk prediction of incident heart failure in community‐dwelling individuals
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2112
Abstract: Cardiovascular biomarkers, particularly natriuretic peptides (NPs) and cardiac troponins (cTn), are important tools for diagnosis, risk stratification and follow-up of patients with heart failure (HF).1 It is well known that both sex and body mass… read more here.
Keywords: circulating levels; natriuretic peptides; heart failure;
Targeted Approach to Distinguish and Determine Absolute Levels of GDF8 and GDF11 in Mouse Serum
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DOI: 10.1002/pmic.201900104
Abstract: Growth differentiation factor 11 (GDF11) is a TGF‐β superfamily circulating factor that regulates cardiomyocyte size in rodents, sharing 90% amino acid sequence identity in the active domains with myostatin (GDF8)—the major determinant of skeletal muscle… read more here.
Keywords: targeted approach; approach distinguish; gdf11; mouse serum ... See more keywords
Association of interleukin 6 -174 G/C polymorphism with coronary artery disease and circulating IL-6 levels: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2021 at "Inflammation Research"
DOI: 10.1007/s00011-021-01505-7
Abstract: Introduction Circulating IL-6 levels and at least one polymorphic form of IL6 gene (IL6 -174 G/C, rs1800795) have been shown to be independently associated with coronary artery disease (CAD) by several investigators. Despite more than… read more here.
Keywords: systematic review; cad; association; circulating levels ... See more keywords
Circulating IL-8 levels are increased in patients with type 2 diabetes and associated with worse inflammatory and cardiometabolic profile
Sign Up to like & getrecommendations! Published in 2017 at "Acta Diabetologica"
DOI: 10.1007/s00592-017-1039-1
Abstract: AimsInterleukin-8 (IL-8) is a chemokine involved in systemic immunity, macrophages infiltration and activation in adipose tissue and may play a significant role in the pathogenesis of type 2 diabetes (T2D) and atherosclerosis. Aims of this… read more here.
Keywords: type diabetes; circulating levels; non diabetic; profile ... See more keywords
Circulating levels of Irisin in obese individuals at genetic risk for Alzheimer’s disease: Correlations with amyloid-β, metabolic, and neurocognitive indices
Sign Up to like & getrecommendations! Published in 2021 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2020.113013
Abstract: Irisin is involved in various metabolic pathways and is suggested to be a potential agent capable of preventing onset of Alzheimer's disease (AD) and ameliorating AD neuropathology and cognitive deficits. In the present study, the… read more here.
Keywords: adfh obesity; group; levels irisin; obesity ... See more keywords
Selective inflammatory propensities in adopted adolescents institutionalized as infants
Sign Up to like & getrecommendations! Published in 2021 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2020.105065
Abstract: This study examined whether early life adversity (ELA) limited to infancy was associated with an increase in circulating levels of proinflammatory cytokines and cellular cytokine responses to three stimulants [lipopolysaccharide (LPS), phytohemagglutinin (PHA), and phorbol… read more here.
Keywords: propensities adopted; adopted adolescents; youth; inflammatory propensities ... See more keywords
Measurement of 1α hydroxycorticosterone in the Japanese banded houndshark, Triakis scyllium, following exposure to a series of stressors.
Sign Up to like & getrecommendations! Published in 2020 at "General and comparative endocrinology"
DOI: 10.1016/j.ygcen.2020.113440
Abstract: An endocrine glucocorticoid response following exposure to a stressor has been well described for many vertebrates. However, despite demonstration of secondary stress responses in a number of elasmobranchs, our understanding of the endocrine control of… read more here.
Keywords: exposure; japanese banded; banded houndshark; following exposure ... See more keywords
Non-coding RNA: Exosomal microRNAs as novel adipokines
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Genetics"
DOI: 10.1038/nrg.2017.14
Abstract: MicroRNAs (miRNAs) produced in adipose tissue cells and released into the circulation encapsulated in small extracellular vesicles (exosomes) can affect gene expression in distant organs, new research shows. These findings might indicate that exosomal miRNAs… read more here.
Keywords: exosomal mirnas; adicerko mice; tissue; adipose tissue ... See more keywords
Decreased Circulating Levels of Dickkopf-1 in Patients with Exudative Age-related Macular Degeneration
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DOI: 10.1038/s41598-017-01119-2
Abstract: Aberrant activation of the Wnt/β-catenin signaling pathway plays a pathogenic role in retinal inflammation and neovascularization. Here, we investigated whether circulating levels of Dickkopf-1 (DKK-1), a specific inhibitor of this pathway, are altered in patients… read more here.
Keywords: exudative amd; levels dickkopf; patients exudative; amd ... See more keywords
High circulating levels of midregional proenkephalin A predict vascular dementia: a population-based prospective study
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DOI: 10.1038/s41598-020-64998-y
Abstract: Midregional Pro-enkephalin A (MR-PENK A) and N-terminal Protachykinin A (NT-PTA) have been associated with vascular dementia. However, the longitudinal relationship between these biomarkers and incident dementia has not been fully investigated. In the population-based Malmö… read more here.
Keywords: population based; circulating levels; vascular dementia; dementia ... See more keywords
P3098Association with coronary high-intensity plaque on T1-weighted magnetic resonance imaging and circulating levels of malondialdehyde-modified low-density lipoprotein
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz745.0174
Abstract: This study aimed to evaluate the association with coronary high-intensity plaque (HIP) on non-contrast T1-weighted magnetic resonance imaging (T1WI) and circulating levels of malondialdehyde-modified low-density lipoprotein (MDA-LDL). A total of 139 patients with coronary artery… read more here.
Keywords: mda ldl; hip; magnetic resonance; intensity ... See more keywords