Articles with "circulating mirna" as a keyword



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Normalization strategies differently affect circulating miRNA profile associated with the training status

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-38505-x

Abstract: MicroRNAs are fine regulators of the whole-body adaptive response but their use as biomarkers is limited by the lack of standardized pre- and post-analytical procedures. This work aimed to compare different normalization approaches for RT-qPCR… read more here.

Keywords: status; circulating mirna; normalization strategies; different normalization ... See more keywords

Variations of circulating miRNA in paediatric patients with Heart Failure supported with Ventricular Assist Device: a pilot study

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-62757-7

Abstract: Circulating miRNAs (c-miRNAs) are promising biomarkers for HF diagnosis and prognosis. There are no studies on HF pediatric patients undergoing VAD-implantation. Aims of this study were: to examine the c-miRNAs profile in HF children; to evaluate… read more here.

Keywords: circulating mirna; study; days vad; variations circulating ... See more keywords
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A9841 The preliminary research on the mechanism of miRNA-296-5p in essential hypertension

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Published in 2018 at "Journal of Hypertension"

DOI: 10.1097/01.hjh.0000548213.07647.8f

Abstract: Objectives: To identify the mechanism of plasma circulating miRNA-296-5p in essential hypertension (EH) patients. Methods: Circulating miRNA-296-5p of plasma samples from 80 EH cases and 80 non-EH cases were analyzed by qRT-PCR, and its biological… read more here.

Keywords: circulating mirna; mechanism; mirna 296; essential hypertension ... See more keywords
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Retinal and circulating miRNA expression patterns in diabetic retinopathy: An in silico and in vivo approach

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Published in 2019 at "British Journal of Pharmacology"

DOI: 10.1111/bph.14665

Abstract: Diabetic retinopathy, a secondary complication of diabetes mellitus, can lead to irreversible vision loss. Currently, no treatment is approved for early phases of diabetic retinopathy. Modifications of the expression pattern of miRNAs could be involved… read more here.

Keywords: retinopathy; diabetic retinopathy; circulating mirna; retinal circulating ... See more keywords
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Key methodological challenges in detecting circulating miRNAs in different biofluids

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Published in 2022 at "Annals of Clinical Biochemistry"

DOI: 10.1177/00045632221129778

Abstract: The technological advancement in diagnostic techniques has immensely improved the capability of predicting disease progression. Yet, there is a great interest in developing newer biomarkers that can enhance disease risk prediction thereby minimising the associated… read more here.

Keywords: methodological challenges; circulating mirnas; challenges detecting; circulating mirna ... See more keywords
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Circulating miRNA in atherosclerosis: a clinical biomarker and early diagnostic tool.

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Published in 2021 at "Current molecular medicine"

DOI: 10.2174/1566524021666210315124438

Abstract: Atherosclerosis, which is a vascular disease, is characterized by narrowing the arteries and forming plaque inside arteries. There is a record 17.5 million associated deaths recorded annually, representing 31% of global death. It has been… read more here.

Keywords: circulating mirna; mir mir; biomarker; mir ... See more keywords
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Circulating miRNA-302 family members as potential biomarkers for the diagnosis of acute heart failure.

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Published in 2018 at "Biomarkers in medicine"

DOI: 10.2217/bmm-2018-0132

Abstract: AIM To explore circulating miRNA-302 family members for acute heart failure (AHF) diagnosis. METHODS Three groups of subjects, in other words, AHF patients, AHF free patients and healthy controls were recruited. Circulating levels of miR-302… read more here.

Keywords: heart; circulating mirna; mirna 302; family members ... See more keywords
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The role of miRNAs in the diagnosis of stable atherosclerosis of different arterial territories: A critical review

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Published in 2022 at "Frontiers in Cardiovascular Medicine"

DOI: 10.3389/fcvm.2022.1040971

Abstract: Atherosclerotic disease is a major cause of morbidity and mortality worldwide. Atherosclerosis may be present in different arterial territories and as a single- or multi-territorial disease. The different phenotypes of atherosclerosis are attributable only in… read more here.

Keywords: arterial territories; different arterial; circulating mirna; atherosclerosis different ... See more keywords
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Evaluation of Circulating miRNA Biomarkers of Testicular Germ Cell Tumors during Therapy and Follow-up―A Copenhagen Experience

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Published in 2020 at "Cancers"

DOI: 10.3390/cancers12030759

Abstract: New microRNA-based serum biomarkers (miRNA-367-3p, -371a-3p, -372-3p, and -373-3p) have shown great potential for the detection of testicular germ cell tumors (TGCTs), but few studies have investigated the clinical utility and performance of these tests… read more here.

Keywords: tumor markers; circulating mirna; testicular germ; germ cell ... See more keywords