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Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-38505-x
Abstract: MicroRNAs are fine regulators of the whole-body adaptive response but their use as biomarkers is limited by the lack of standardized pre- and post-analytical procedures. This work aimed to compare different normalization approaches for RT-qPCR…
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Keywords:
status;
circulating mirna;
normalization strategies;
different normalization ... See more keywords
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Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-62757-7
Abstract: Circulating miRNAs (c-miRNAs) are promising biomarkers for HF diagnosis and prognosis. There are no studies on HF pediatric patients undergoing VAD-implantation. Aims of this study were: to examine the c-miRNAs profile in HF children; to evaluate…
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Keywords:
circulating mirna;
study;
days vad;
variations circulating ... See more keywords
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Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548213.07647.8f
Abstract: Objectives: To identify the mechanism of plasma circulating miRNA-296-5p in essential hypertension (EH) patients. Methods: Circulating miRNA-296-5p of plasma samples from 80 EH cases and 80 non-EH cases were analyzed by qRT-PCR, and its biological…
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Keywords:
circulating mirna;
mechanism;
mirna 296;
essential hypertension ... See more keywords
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Published in 2019 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14665
Abstract: Diabetic retinopathy, a secondary complication of diabetes mellitus, can lead to irreversible vision loss. Currently, no treatment is approved for early phases of diabetic retinopathy. Modifications of the expression pattern of miRNAs could be involved…
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Keywords:
retinopathy;
diabetic retinopathy;
circulating mirna;
retinal circulating ... See more keywords
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Published in 2022 at "Annals of Clinical Biochemistry"
DOI: 10.1177/00045632221129778
Abstract: The technological advancement in diagnostic techniques has immensely improved the capability of predicting disease progression. Yet, there is a great interest in developing newer biomarkers that can enhance disease risk prediction thereby minimising the associated…
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Keywords:
methodological challenges;
circulating mirnas;
challenges detecting;
circulating mirna ... See more keywords
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Published in 2021 at "Current molecular medicine"
DOI: 10.2174/1566524021666210315124438
Abstract: Atherosclerosis, which is a vascular disease, is characterized by narrowing the arteries and forming plaque inside arteries. There is a record 17.5 million associated deaths recorded annually, representing 31% of global death. It has been…
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Keywords:
circulating mirna;
mir mir;
biomarker;
mir ... See more keywords
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Published in 2018 at "Biomarkers in medicine"
DOI: 10.2217/bmm-2018-0132
Abstract: AIM To explore circulating miRNA-302 family members for acute heart failure (AHF) diagnosis. METHODS Three groups of subjects, in other words, AHF patients, AHF free patients and healthy controls were recruited. Circulating levels of miR-302…
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Keywords:
heart;
circulating mirna;
mirna 302;
family members ... See more keywords
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Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.1040971
Abstract: Atherosclerotic disease is a major cause of morbidity and mortality worldwide. Atherosclerosis may be present in different arterial territories and as a single- or multi-territorial disease. The different phenotypes of atherosclerosis are attributable only in…
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Keywords:
arterial territories;
different arterial;
circulating mirna;
atherosclerosis different ... See more keywords
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Published in 2020 at "Cancers"
DOI: 10.3390/cancers12030759
Abstract: New microRNA-based serum biomarkers (miRNA-367-3p, -371a-3p, -372-3p, and -373-3p) have shown great potential for the detection of testicular germ cell tumors (TGCTs), but few studies have investigated the clinical utility and performance of these tests…
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Keywords:
tumor markers;
circulating mirna;
testicular germ;
germ cell ... See more keywords