The diversity of circulating neutrophils in cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Immunobiology"
DOI: 10.1016/j.imbio.2016.02.001
Abstract: Neutrophils, the most abundant leukocyte in human circulation are being more and more recognized as part of the immune reaction to cancer. In the last years, the understanding that neutrophils possess a dual role in… read more here.
Keywords: sub populations; diversity circulating; neutrophils cancer; circulating neutrophils ... See more keywords
DOP126 Circulating neutrophils exhibit distinct transcriptional and maturity changes in CD and UC that relate to pathogenic Th1/17 CD4+ memory T cell responses
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjae190.0165
Abstract: Neutrophils are key players in intestinal damage in Crohn’s disease (CD) and ulcerative colitis (UC) but their immunological role in disease heterogeneity is largely overlooked. In both diseases, mature circulating neutrophils enter the intestinal tissue… read more here.
Keywords: circulating neutrophils; pathogenic th1; maturity; expression ... See more keywords
P0691 Impact of Ozanimod (OZA) on Circulating Neutrophils: Results from the Phase 3 Japanese True North (J-TN) Study of Patients (Pts) With Moderately to Severely Active Ulcerative Colitis (UC)
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjae190.0865
Abstract: OZA was approved for treatment (tx) of moderately to severely active UC in adults based on TN study results. Increases in circulating neutrophils are an indicator of systemic inflammation, and increased infiltration of activated neutrophils… read more here.
Keywords: treatment; circulating neutrophils; cpa9 hne; hne levels ... See more keywords
Peripheral priming induces plastic transcriptomic and proteomic responses in circulating neutrophils required for pathogen containment
Sign Up to like & getrecommendations! Published in 2024 at "Science Advances"
DOI: 10.1126/sciadv.adl1710
Abstract: Neutrophils rapidly respond to inflammation and infection, but to which degree their functional trajectories after mobilization from the bone marrow are shaped within the circulation remains vague. Experimental limitations have so far hampered neutrophil research… read more here.
Keywords: circulating neutrophils; priming induces; peripheral priming; pathogen containment ... See more keywords
P52 Elevated intratumour neutrophils associate with improved treatment responses and prognosis in patients with HCC
Sign Up to like & getrecommendations! Published in 2020 at "Gut"
DOI: 10.1136/gutjnl-2020-basl.62
Abstract: Hepatocellular carcinomas (HCC) develop on a background of chronic liver inflammation. Neutrophils are key mediators of the tumour immune microenvironment. Elevated circulating neutrophils in HCC patients is independently associated with poorer survival, while neutrophil depletion… read more here.
Keywords: number neutrophils; patients hcc; treatment; intratumour neutrophils ... See more keywords
P01.14 Excessive biological ageing of circulating neutrophils in cancer promotes tumor progression
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-itoc7.27
Abstract: Background Beyond their well-established role in host defense, neutrophils are increasingly recognized to contribute to the pathogenesis of malignant tumors. Recently, ageing of mature neutrophils in the systemic circulation has been identified to be critical… read more here.
Keywords: none; biological ageing; cancer; ageing circulating ... See more keywords
Long-term Interactions of Circulating Neutrophils with Titanium Implants, the Role of Platelets in Regulation of Leukocyte Function
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms221810060
Abstract: Despite the fact that different biomaterials are widely used in many biomedical applications, they can still cause side effects. Therefore, our aim was to assess neutrophil activity during the inflammatory phase of the repair process… read more here.
Keywords: term interactions; long term; interactions circulating; neutrophils titanium ... See more keywords