Evaluation of Comparative Surveillance Strategies of Circulating Tumor DNA, Imaging, and Carcinoembryonic Antigen Levels in Patients With Resected Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.1093
Abstract: Key Points Question Is serial analysis of circulating tumor DNA (ctDNA) associated with improved sensitivity and earlier detection of recurrence compared with standard imaging and evaluation of carcinoembryonic antigen (CEA) levels per National Comprehensive Cancer… read more here.
Keywords: circulating tumor; resected colorectal; colorectal cancer; tumor dna ... See more keywords
Characterization of single circulating tumor cells
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12662
Abstract: “Liquid biopsy” has been introduced for the analysis of circulating tumor cells (CTCs) in the blood of cancer patients, and this new diagnostic approach has received enormous attention. CTCs are derived from primary tumors and… read more here.
Keywords: tumor cells; single circulating; circulating tumor; characterization single ... See more keywords
High‐throughput isolation of circulating tumor DNA: a comparison of automated platforms
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12415
Abstract: The emerging interest in circulating tumor DNA (ctDNA) analyses for clinical trials has necessitated the development of a high‐throughput method for fast, reproducible, and efficient isolation of ctDNA. Currently, the majority of ctDNA studies use… read more here.
Keywords: dna; circulating tumor; isolation; tumor dna ... See more keywords
AR splice variants in circulating tumor cells of patients with castration‐resistant prostate cancer: relation with outcome to cabazitaxel
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12529
Abstract: The androgen receptor splice variant (AR‐V) 7 in circulating tumor cells (CTCs) is a predictor for resistance to anti‐AR‐targeted treatment, but not to taxane‐based chemotherapy in metastatic castration‐resistant prostate cancer (mCRPC). In this study, we… read more here.
Keywords: prostate; tumor cells; prostate cancer; circulating tumor ... See more keywords
Clinical utility of circulating tumor cells: an update
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12869
Abstract: The prognostic role of circulating tumor cells (CTCs) has been clearly demonstrated in many types of cancer. However, their roles in diagnostic and treatment strategies remain to be defined. In this review, we present an… read more here.
Keywords: utility circulating; clinical utility; utility; tumor cells ... See more keywords
Early circulating tumor DNA dynamics as a pan‐tumor biomarker for long‐term clinical outcome in patients treated with durvalumab and tremelimumab
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13349
Abstract: There is an urgent need to identify biomarkers of early response that can accurately predict the benefit of immune checkpoint inhibitors (ICI). Patients receiving durvalumab/tremelimumab had tumor samples sequenced before treatment (baseline) to identify variants… read more here.
Keywords: circulating tumor; biomarker; tumor; treatment ... See more keywords
An Implantable Magnetic Vascular Scaffold for Circulating Tumor Cell Removal In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202207870
Abstract: An integrated trapped device (ITD) capable of removal of circulating tumor cells (CTCs) can assuage or even prevent metastasis. However, adhesion repertoires are ordinarily neglected in the design of ITDs, possibly leading to the omission… read more here.
Keywords: circulating tumor; vascular; itd; vivo ... See more keywords
Tracking Neoantigens by Personalized Circulating Tumor DNA Sequencing during Checkpoint Blockade Immunotherapy in Non‐Small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Science"
DOI: 10.1002/advs.201903410
Abstract: Abstract The evolutionary dynamics of tumor‐associated neoantigens carry information about drug sensitivity and resistance to the immune checkpoint blockade (ICB). However, the spectrum of somatic mutations is highly heterogeneous among patients, making it difficult to… read more here.
Keywords: checkpoint blockade; small cell; circulating tumor; non small ... See more keywords
Prognostic impact of circulating tumor cells in patients with soft‐tissue sarcomas: a prospective study
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Communications"
DOI: 10.1002/cac2.12389
Abstract: Dear Editor, Sarcomas represent a heterogenous group of tumors accounting for about 1% of cancer in adults and 15% in children [1]. However, despite adequate locoregional treatment, up to 40% of patients develop metastatic disease.… read more here.
Keywords: circulating tumor; soft tissue; tumor cells; patients soft ... See more keywords
μ‐opioid receptor agonist facilitates circulating tumor cell formation in bladder cancer via the MOR/AKT/Slug pathway: a comprehensive study including randomized controlled trial
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Communications"
DOI: 10.1002/cac2.12408
Abstract: μ‐opioid receptor agonists (MORAs) are indispensable for analgesia in bladder cancer (BC) patients, both during surgery and for chronic pain treatment. Whether MORAs affect BC progression and metastasis remains largely unknown. This study focused on… read more here.
Keywords: circulating tumor; bladder cancer; cancer; opioid receptor ... See more keywords
The prognostic significance of circulating tumor cells in head and neck and non‐small‐cell lung cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1832
Abstract: Tumor biopsy is the gold standard for the assessment of clinical biomarkers for treatment. However, tumors change dynamically in response to therapy, and there remains a need for a more representative biomarker that can be… read more here.
Keywords: tumor cells; circulating tumor; head neck; cancer ... See more keywords