Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population
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DOI: 10.1002/hep.31238
Abstract: We hypothesized that a genetic risk score (GRS) for fatty liver disease influences the risk of cirrhosis and hepatocellular carcinoma (HCC). Three genetic variants (patatin‐like phospholipase domain–containing protein 3 [PNPLA3] p.I148M; transmembrane 6, superfamily member… read more here.
Keywords: hepatocellular carcinoma; pnpla3; risk cirrhosis; cirrhosis hepatocellular ... See more keywords
Assessing the performance of ChatGPT in answering questions regarding cirrhosis and hepatocellular carcinoma
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DOI: 10.1101/2023.02.06.23285449
Abstract: Background: Patients with cirrhosis and hepatocellular carcinoma (HCC) require extensive care. Personalized education can improve their outcomes. ChatGPT (Generative Pre-trained Transformer), a natural language processing model, has shown potential to provide professional yet patient-freindly responses.… read more here.
Keywords: hepatocellular carcinoma; cirrhosis hepatocellular; chatgpt; knowledge ... See more keywords
Missed opportunities for diagnosis of hepatitis B and C in individuals diagnosed with decompensated cirrhosis or hepatocellular carcinoma.
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DOI: 10.1111/jgh.16162
Abstract: BACKGROUND AND AIM To assess utilization of health care services in people with decompensated cirrhosis (DC) or hepatocellular carcinoma (HCC) and a "late diagnosis" of hepatitis B or hepatitis C. METHODS Hepatitis B and C… read more here.
Keywords: missed opportunities; hepatocellular carcinoma; diagnosis; cirrhosis hepatocellular ... See more keywords
Estimating the attributable fraction of cirrhosis and hepatocellular carcinoma due to hepatitis B and C
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DOI: 10.1111/jvh.13545
Abstract: A goal of the WHO strategy on the elimination of hepatitis as a public threat is a 65% reduction in the attributable mortality. Deaths related to hepatitis B and C infections are mostly due to… read more here.
Keywords: hepatocellular carcinoma; hepatitis; cirrhosis; cirrhosis hepatocellular ... See more keywords
Mortality from cirrhosis and hepatocellular carcinoma in Western Europe over the last 40 years
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DOI: 10.1111/liv.13371
Abstract: Cirrhosis (LC) and hepatocellular carcinoma (HCC) are highly prevalent in Europe, with accompanying high mortality rates and social costs. As epidemiological data on these diseases are scarce, age‐standardized death rate (ASDR) can serve as an… read more here.
Keywords: hepatocellular carcinoma; mortality cirrhosis; cirrhosis hepatocellular; europe ... See more keywords
Predictors of liver cirrhosis and hepatocellular carcinoma among perioperative survivors of the Fontan operation
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DOI: 10.1136/heartjnl-2022-320940
Abstract: Objective Fontan-associated liver disease (FALD) is widely recognised as a common complication in patients long after the Fontan operation. However, data on the predictors of FALD that can guide its screening and management are lacking.… read more here.
Keywords: hepatocellular carcinoma; liver cirrhosis; operation; cirrhosis hepatocellular ... See more keywords
Long-term change in incidence and risk factors of cirrhosis and hepatocellular carcinoma in Crete, Greece: a 25-year study
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DOI: 10.20524/aog.2017.0135
Abstract: Background No sequential long-term data exist for Greece on the etiological evolution and incidence of cirrhosis and hepatocellular carcinoma. Therefore, we studied their etiological evolution over a period of 25 years in the island of… read more here.
Keywords: incidence; hepatocellular carcinoma; risk; carcinoma ... See more keywords
TBX5 Variants are Associated with Susceptibility to and the Incidence of Liver Cirrhosis and Hepatocellular Carcinoma in the Chinese Population: A Multicenter and Follow-Up Study
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DOI: 10.2147/idr.s410151
Abstract: Purpose Liver cirrhosis (LC) and hepatocellular carcinoma (HCC) are progressions affected by genetic predispositions, and persistent hepatitis B virus infection also demonstrates genetic susceptibility. All HBV-related outcomes have been compared in parallel to identify risk… read more here.
Keywords: hepatocellular carcinoma; liver cirrhosis; infection; cirrhosis hepatocellular ... See more keywords