Predicting HCC Response to Multikinase Inhibitors With In Vivo Cirrhotic Mouse Model for Personalized Therapy
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DOI: 10.1016/j.jcmgh.2020.12.009
Abstract: Background & Aims Hepatocellular carcinoma (HCC) arises in a cirrhotic, pro-angiogenic microenvironment. Inhibiting angiogenesis is a key mode of action of multikinase inhibitors and current non-cirrhotic models are unable to predict treatment response. We present… read more here.
Keywords: cirrhotic model; response; multikinase inhibitors; model ... See more keywords