Articles with "cirs 122" as a keyword



Photo by nci from unsplash

Exosome‐delivered circRNA promotes glycolysis to induce chemoresistance through the miR‐122‐PKM2 axis in colorectal cancer

Sign Up to like & get
recommendations!
Published in 2020 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12629

Abstract: Malignant tumors, including colorectal cancer (CRC), usually rely on ATP generation through aerobic glycolysis for both rapid growth and chemotherapy resistance. The M2 isoform of pyruvate kinase (PKM2) has a key role in catalyzing glycolysis,… read more here.

Keywords: glycolysis; pkm2; colorectal cancer; 122 pkm2 ... See more keywords