Up modulation of dose‐averaged linear energy transfer by simultaneous integrated boost in carbon‐ion radiotherapy for pancreatic carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.14279
Abstract: Abstract Background Local recurrence in locally advanced pancreatic cancer (LAPC) after carbon‐ion radiotherapy (CIRT) may partly attribute to low dose‐averaged linear energy transfer (LETd), despite high CIRT dose. Purpose This study aimed to investigate the… read more here.
Keywords: averaged linear; dose averaged; carbon ion; cirt ... See more keywords
Comparison of clinical outcomes between carbon ion radiotherapy and X-ray radiotherapy for reirradiation in locoregional recurrence of rectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-05809-4
Abstract: Carbon ion radiotherapy (CIRT) has garnered interest for the treatment of locoregional rectal cancer recurrence. No study has compared CIRT and X-ray radiotherapy (XRT) for reirradiation (reRT) in such cases. We analyzed and compared the… read more here.
Keywords: cirt; recurrence; carbon ion; rectal cancer ... See more keywords
Carbon ion radiotherapy triggers immunogenic cell death and sensitizes melanoma to anti-PD-1 therapy in mice
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DOI: 10.1080/2162402x.2022.2057892
Abstract: ABSTRACT Carbon ion radiotherapy (CIRT) is an emerging type of radiotherapy for the treatment of solid tumors. In recent years, evidence accumulated that CIRT improves the therapeutic outcome in patients with otherwise poor response to… read more here.
Keywords: cell death; radiotherapy; immunogenic cell; cirt ... See more keywords
Clinical results of carbon-ion radiotherapy for stage I non-small cell lung cancer with concomitant interstitial lung disease: a Japanese national registry study (J-CROS-LUNG).
Sign Up to like & getrecommendations! Published in 2023 at "Journal of radiation research"
DOI: 10.1093/jrr/rrad008
Abstract: Anti-cancer treatments for lung cancer patients with interstitial lung disease (ILD) are challenging. The treatment options for ILD are often limited because of concerns that treatments can cause acute exacerbation (AE) of ILD. This study… read more here.
Keywords: lung cancer; disease; cirt; lung ... See more keywords
Updated long‐term outcomes after carbon‐ion radiotherapy for primary renal cell carcinoma
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DOI: 10.1111/cas.13727
Abstract: Long‐term oncological outcomes for primary renal cell carcinoma (RCC) treated with carbon‐ion radiotherapy (CIRT) are poorly understood. Patients with primary RCC were treated with 12 or 16‐fraction CIRT at The Hospital of the National Institute… read more here.
Keywords: renal cell; primary renal; term; cirt ... See more keywords
Carbon ion radiation therapy for sinonasal malignancies: Promising results from 2282 cases from the real world
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DOI: 10.1111/cas.14650
Abstract: The aim of this study is to compare the effectiveness of carbon ion radiation therapy (CIRT), proton radiation therapy (PRT), and photon‐based intensity‐modulated radiation therapy (IMRT) in the treatment of sinonasal malignancies. We identified studies… read more here.
Keywords: imrt; radiation therapy; group; cirt ... See more keywords
Conversion surgery for initially unresectable locally advanced pancreatic ductal adenocarcinoma after chemotherapy followed by carbon-ion radiotherapy: a case report
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medical Case Reports"
DOI: 10.1186/s13256-023-04311-3
Abstract: Recent advances in chemotherapy and chemoradiotherapy have enabled conversion surgery (CS) to be performed for selected patients with initially unresectable locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC). Many studies indicate CS might extend the survival… read more here.
Keywords: initially unresectable; surgery; radiotherapy; cirt ... See more keywords
Evaluation of EpiSwitch in predicting immunotherapy response in hepatocellular carcinoma and gastrointestinal tumors.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.4_suppl.623
Abstract: 623 Background: The EpiSwitch Checkpoint Inhibitor Response Test (CiRT) is a blood-based assay that analyzes DNA conformations in immune cells to predict responses to immune checkpoint inhibitors (ICIs) targeting PD-L1/PD-1. CiRT has demonstrated superior predictive… read more here.
Keywords: gastrointestinal tumors; response; immunotherapy response; cirt ... See more keywords
Prospective clinical trial of 12-fraction carbon-ion radiotherapy for primary renal cell carcinoma
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DOI: 10.18632/oncotarget.26539
Abstract: The aims of this study were to clarify the safety and efficacy of 12-fraction carbon-ion radiotherapy (CIRT) for primary renal cell carcinoma (RCC) and to confirm the recommended dose in a prospective clinical trial. This… read more here.
Keywords: clinical trial; trial; ion radiotherapy; cirt ... See more keywords
In Vivo Dosimetry in the Urethra During Prostate Carbon Ion Radiotherapy
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DOI: 10.21873/anticanres.16389
Abstract: Background/Aim: In vivo dosimetry can prevent dose delivery errors by directly measuring the dose of radiation administered to a patient. However, a method for in vivo dosimetry during carbon ion radiotherapy (CIRT) has not been… read more here.
Keywords: carbon ion; vivo dosimetry; vivo; prostate ... See more keywords
Effectiveness of Carbon Ion Radiotherapy for Bone and Soft Tissue Sarcoma in Older Patients
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DOI: 10.21873/anticanres.16977
Abstract: Background/Aim: The aging population is expected to increase the occurrences of bone sarcoma (BS) and soft tissue sarcoma (STS). Carbon ion radiotherapy (CIRT) is reported to be effective for BS and several STSs. However, the… read more here.
Keywords: tissue sarcoma; carbon ion; cirt; older patients ... See more keywords