Determination of Amide cis/trans Isomers in N‐Acetyl‐d‐glucosamine: Tailored NMR Analysis of the N‐Acetyl Group Conformation
Sign Up to like & getrecommendations! Published in 2022 at "Chembiochem"
DOI: 10.1002/cbic.202200338
Abstract: N‐Acetyl‐d‐glucosamine (GlcNAc) is one of the most common amino sugars in nature, but the conformation of its N‐acetyl group has drawn little attention. We report herein the first identification of NH protons of the amide… read more here.
Keywords: conformation; cis; amide cis; acetyl group ... See more keywords
Re‐Programming and Optimization of a L‐Proline cis‐4‐Hydroxylase for the cis‐3‐Halogenation of its Native Substrate
Sign Up to like & getrecommendations! Published in 2021 at "ChemCatChem"
DOI: 10.1002/cctc.202100591
Abstract: Non‐heme iron/α‐ketoglutarate dependent halogenases acting on freestanding substrates catalyze the regio‐ and stereoselective halogenation of inactivated C(sp3)‐H bonds. Yet, with only a handful of these halogenases characterized, the biosynthetic potential of enzymatic radical halogenation remains… read more here.
Keywords: cis; proline cis; halogenation; cis hydroxylase ... See more keywords
Melatonin is effective in attenuating cisplatin-induced neurotoxicity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23075
Abstract: Cisplatin (Cis) is a chemotherapeutic agent that has many side effects. Neurotoxicity is one of the most important of these side effects. Oxidative stress and neuroinflammation are the best-known mechanisms in the pathogenesis of neurotoxicity… read more here.
Keywords: vehicle; mel; cis; induced neurotoxicity ... See more keywords
Clemizole hydrochloride, a potent TRPC5 calcium channel inhibitor, prevents cisplatin-induced nephrotoxicity in Spraque-Dawley rats.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23372
Abstract: Cis-diamminedichloroplatinum (II) (cisplatin, Cis) is widely employed to treat several types of cancer. It has many important toxic side effects; one of the most important of which is nephrotoxicity. Clemizole hydrochloride (Clem) as the most… read more here.
Keywords: clem; clemizole hydrochloride; doses clem; cis ... See more keywords
Responses of MAC-T Cells to Inhibited Stearoyl-CoA Desaturase 1 during cis-9, trans-11 Conjugated Linoleic Acid Synthesis.
Sign Up to like & getrecommendations! Published in 2018 at "Lipids"
DOI: 10.1002/lipd.12077
Abstract: Cis-9-conjugated, trans-11-conjugated linoleic acid (CLA) is known for its positive activities on human health. The synthesis of cis-9, trans-11 CLA in mammary glands is generally thought to be catalyzed by stearoyl-CoA desaturase 1 (SCD1), but… read more here.
Keywords: cis; mac cells; coa; cis trans ... See more keywords
Controlled Polymerization of Isoprene with Chromium-Based Metal-Organic Framework Catalysts: Switching from Cyclic to cis-1,4-Selectivity Depending on Activator.
Sign Up to like & getrecommendations! Published in 2018 at "Macromolecular rapid communications"
DOI: 10.1002/marc.201800002
Abstract: Chromium-based metal-organic framework (MOF) Cr-MIL-100/101 activated by activator and aluminum trialkyl compound serve as unique, highly efficient heterogeneous single-site catalysts for the controlled polymerization of isoprene, which not only exhibit quasi-living nature in isoprene polymerization… read more here.
Keywords: cis; chromium based; polymerization; activator ... See more keywords
Validity of the posterior limbic circuitry hypothesis as a basis for the cingulate island sign
Sign Up to like & getrecommendations! Published in 2019 at "Movement Disorders"
DOI: 10.1002/mds.27679
Abstract: We read with great interest the articles by Nedelska and colleagues showing significantly larger amounts of tau deposition in posterior cortical atrophy (PCA) than in dementia with Lewy bodies (DLB) as seen by AV-1451 PET.… read more here.
Keywords: cis; pcc; cingulate; pca dlb ... See more keywords
Assessment of TDDFT- and CIS-based methods for calculating fluorescence spectra of (dibenzoylmethanato)boron difluoride exciplexes with aromatic hydrocarbons
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-017-3341-9
Abstract: The applicabilities of various CIS- and TDDFT-based procedures to the calculation of the fluorescence spectra of DBMBF2 exciplexes with aromatic hydrocarbons are analyzed. It is shown that a reasonable agreement between the calculated and experimental… read more here.
Keywords: cis; exciplexes aromatic; fluorescence; fluorescence spectra ... See more keywords
Structure-Based Stepwise Screening of PPARγ Antagonists as Potential Competitors with NCOA1 Coactivator Peptide for PPARγ CIS Site
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-018-9782-x
Abstract: The small-molecule modulators (agonists and antagonists) of peroxisome proliferator-activated receptor-γ (PPARγ) have been widely used to treat metabolic, cardiovascular and inflammatory diseases such as Type-2 diabetes and heart failure. Existing PPARγ modulators are all developed… read more here.
Keywords: ppar; cis; ppar cis; cis site ... See more keywords
ERβ modulates genistein’s cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03505-y
Abstract: As one of the typical food-derived phytoestrogens, genistein (GEN) could bind to estrogen receptor (ER) and was reported to be closely related to breast cancer. Our former research showed that GEN interfered with the anti-tumor… read more here.
Keywords: cis; mda 231; gen; breast cancer ... See more keywords
Synthesis and antimicrobial activities of some novel diastereoselective monocyclic cis-β-lactams using 2-ethoxy carbonyl DCPN as a carboxylic acid activator
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Diversity"
DOI: 10.1007/s11030-020-10099-x
Abstract: A series of novel monocyclic cis-β-lactams were prepared from phenoxyacetic acid as ketene source and imines derived from 1-chloro-3,4-dihydronaphthalene-2-carbaldehyde and respective amine using ethyl 4,5-dichloro-6-oxopyridazine-1(6H)-carboxylate (or 2-ethoxy carbonyl DCPN) as a carboxylic acid activator. This… read more here.
Keywords: cis; ethoxy carbonyl; carbonyl dcpn; monocyclic cis ... See more keywords