Determination of Amide cis/trans Isomers in N‐Acetyl‐d‐glucosamine: Tailored NMR Analysis of the N‐Acetyl Group Conformation
Sign Up to like & getrecommendations! Published in 2022 at "Chembiochem"
DOI: 10.1002/cbic.202200338
Abstract: N‐Acetyl‐d‐glucosamine (GlcNAc) is one of the most common amino sugars in nature, but the conformation of its N‐acetyl group has drawn little attention. We report herein the first identification of NH protons of the amide… read more here.
Keywords: conformation; cis; amide cis; acetyl group ... See more keywords
Re‐Programming and Optimization of a L‐Proline cis‐4‐Hydroxylase for the cis‐3‐Halogenation of its Native Substrate
Sign Up to like & getrecommendations! Published in 2021 at "ChemCatChem"
DOI: 10.1002/cctc.202100591
Abstract: Non‐heme iron/α‐ketoglutarate dependent halogenases acting on freestanding substrates catalyze the regio‐ and stereoselective halogenation of inactivated C(sp3)‐H bonds. Yet, with only a handful of these halogenases characterized, the biosynthetic potential of enzymatic radical halogenation remains… read more here.
Keywords: cis; proline cis; halogenation; cis hydroxylase ... See more keywords
Melatonin is effective in attenuating cisplatin-induced neurotoxicity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23075
Abstract: Cisplatin (Cis) is a chemotherapeutic agent that has many side effects. Neurotoxicity is one of the most important of these side effects. Oxidative stress and neuroinflammation are the best-known mechanisms in the pathogenesis of neurotoxicity… read more here.
Keywords: vehicle; mel; cis; induced neurotoxicity ... See more keywords
Clemizole hydrochloride, a potent TRPC5 calcium channel inhibitor, prevents cisplatin-induced nephrotoxicity in Spraque-Dawley rats.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23372
Abstract: Cis-diamminedichloroplatinum (II) (cisplatin, Cis) is widely employed to treat several types of cancer. It has many important toxic side effects; one of the most important of which is nephrotoxicity. Clemizole hydrochloride (Clem) as the most… read more here.
Keywords: clem; clemizole hydrochloride; doses clem; cis ... See more keywords
Responses of MAC-T Cells to Inhibited Stearoyl-CoA Desaturase 1 during cis-9, trans-11 Conjugated Linoleic Acid Synthesis.
Sign Up to like & getrecommendations! Published in 2018 at "Lipids"
DOI: 10.1002/lipd.12077
Abstract: Cis-9-conjugated, trans-11-conjugated linoleic acid (CLA) is known for its positive activities on human health. The synthesis of cis-9, trans-11 CLA in mammary glands is generally thought to be catalyzed by stearoyl-CoA desaturase 1 (SCD1), but… read more here.
Keywords: cis; mac cells; coa; cis trans ... See more keywords
Controlled Polymerization of Isoprene with Chromium-Based Metal-Organic Framework Catalysts: Switching from Cyclic to cis-1,4-Selectivity Depending on Activator.
Sign Up to like & getrecommendations! Published in 2018 at "Macromolecular rapid communications"
DOI: 10.1002/marc.201800002
Abstract: Chromium-based metal-organic framework (MOF) Cr-MIL-100/101 activated by activator and aluminum trialkyl compound serve as unique, highly efficient heterogeneous single-site catalysts for the controlled polymerization of isoprene, which not only exhibit quasi-living nature in isoprene polymerization… read more here.
Keywords: cis; chromium based; polymerization; activator ... See more keywords
Supersoft Polymer Melts in Binary Blends of Bottlebrush cis-1,4-Polyfarnesene and cis-1,4-Polyisoprene.
Sign Up to like & getrecommendations! Published in 2024 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202400551
Abstract: Binary blends of polyterpenes are employed comprising cis-1,4-polyfarnesene (PF) with a bottlebrush architecture, and linear cis-1,4-polyisoprene (PI) as model systems toward supersoft polymer melts. The bottlebrush PF results in a low plateau modulus ( G… read more here.
Keywords: cis; binary blends; supersoft polymer; cis polyfarnesene ... See more keywords
Validity of the posterior limbic circuitry hypothesis as a basis for the cingulate island sign
Sign Up to like & getrecommendations! Published in 2019 at "Movement Disorders"
DOI: 10.1002/mds.27679
Abstract: We read with great interest the articles by Nedelska and colleagues showing significantly larger amounts of tau deposition in posterior cortical atrophy (PCA) than in dementia with Lewy bodies (DLB) as seen by AV-1451 PET.… read more here.
Keywords: cis; pcc; cingulate; pca dlb ... See more keywords
Digital volumetric assessment of CIS and tumor mass compliments conventional histopathological assessment in muscle-invasive urothelial bladder cancer
Sign Up to like & getrecommendations! Published in 2024 at "Virchows Archiv"
DOI: 10.1007/s00428-024-03875-9
Abstract: Carcinoma in situ (CIS) of the bladder is a known parameter regarding the prognosis and recurrence tendency of urothelial carcinomas. Nevertheless, there is little evidence whether the amount of CIS or other precursor lesions, as… read more here.
Keywords: cis; assessment; muscle invasive; tumor ... See more keywords
Assessment of TDDFT- and CIS-based methods for calculating fluorescence spectra of (dibenzoylmethanato)boron difluoride exciplexes with aromatic hydrocarbons
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-017-3341-9
Abstract: The applicabilities of various CIS- and TDDFT-based procedures to the calculation of the fluorescence spectra of DBMBF2 exciplexes with aromatic hydrocarbons are analyzed. It is shown that a reasonable agreement between the calculated and experimental… read more here.
Keywords: cis; exciplexes aromatic; fluorescence; fluorescence spectra ... See more keywords
Structure-Based Stepwise Screening of PPARγ Antagonists as Potential Competitors with NCOA1 Coactivator Peptide for PPARγ CIS Site
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-018-9782-x
Abstract: The small-molecule modulators (agonists and antagonists) of peroxisome proliferator-activated receptor-γ (PPARγ) have been widely used to treat metabolic, cardiovascular and inflammatory diseases such as Type-2 diabetes and heart failure. Existing PPARγ modulators are all developed… read more here.
Keywords: ppar; cis; ppar cis; cis site ... See more keywords