Biotin-tagged cis-dichlorido-oxidovanadium(IV) complex for DNA crosslinking and photo-induced apoptotic cytotoxicity
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DOI: 10.1016/j.ica.2021.120629
Abstract: Abstract Cis-dichlorido-oxidovanadium(IV) complexes [VO(dpa/L1)Cl2] (1, 2) of dipicolylamine (dpa, 1 as control species) and 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid (biotin)-appended dpa (L1, 2 as active species) were prepared and their anticancer activity studied. Single crystal X-ray diffraction analysis… read more here.
Keywords: biotin; cis dichlorido; dna crosslinking; photo induced ... See more keywords