Articles with "cisd2 essential" as a keyword



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Cisd2 is essential to delaying cardiac aging and to maintaining heart functions

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Published in 2019 at "PLoS Biology"

DOI: 10.1371/journal.pbio.3000508

Abstract: CDGSH iron-sulfur domain-containing protein 2 (Cisd2) is pivotal to mitochondrial integrity and intracellular Ca2+ homeostasis. In the heart of Cisd2 knockout mice, Cisd2 deficiency causes intercalated disc defects and leads to degeneration of the mitochondria… read more here.

Keywords: heart; cisd2 essential; cardiac aging; cisd2 ... See more keywords