Abstract 1689: Ovarian tumor-induced CISH expression is an immune checkpoint for NK cells
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-1689
Abstract: Background: Non-specificity of symptoms in early stages of ovarian cancer (OVCA), lack of an early detection test and inefficient chemotherapy regimens lead to frequent recurrence and high mortality rates. OVCA differs from other malignancies as… read more here.
Keywords: immune checkpoint; checkpoint cells; late stages; cish expression ... See more keywords
CISH Expression Is Associated with Metastasis-Free Interval in Triple-Negative Breast Cancer and Refines the Prognostic Value of PDL1 Expression
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14143356
Abstract: Simple Summary CISH is a member of the suppressors of cytokine signaling (SOCS) family of proteins and an important negative regulator of T cells and NK cells signaling and function. In this study, analyzing 1936… read more here.
Keywords: pdl1; triple negative; expression; cish expression ... See more keywords