Forty years of cisplatin-based chemotherapy in muscle-invasive bladder cancer: are we understanding how, who and when?
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DOI: 10.1007/s00345-018-2544-8
Abstract: PurposeFor 40 years cisplatin-based chemotherapy has been administered to patients with muscle-invasive bladder cancer (MIBC). The best evidence of its efficacy is found in the context of neoadjuvant chemotherapy (NAC). However, the benefit to the… read more here.
Keywords: chemotherapy; invasive bladder; cisplatin based; muscle invasive ... See more keywords
The evaluation of adding induction chemotherapy to concurrent chemoradiotherapy for locally advanced nasopharyngeal carcinoma: a meta-analysis
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DOI: 10.1007/s00405-020-06218-x
Abstract: We performed a meta-analysis to compare the efficacy and safety of induction chemotherapy (IC) followed by cisplatin-based concurrent chemoradiotherapy (CCRT) versus cisplatin-based CCRT for patients with locally advanced nasopharyngeal carcinoma (LA-NPC). We systematically searched PubMed,… read more here.
Keywords: cisplatin based; induction chemotherapy; based ccrt; survival ... See more keywords
Downregulation of topoisomerase 1 and 2 with acriflavine sensitizes bladder cancer cells to cisplatin-based chemotherapy.
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DOI: 10.1007/s11033-021-07087-1
Abstract: BACKGROUND Resistance to cisplatin is a major obstacle to effective treatment of bladder cancer (BC). The present study aimed to determine whether a combination of acriflavine (ACF) with cisplatin could potentiate the antitumor property of… read more here.
Keywords: based chemotherapy; cells cisplatin; cisplatin based; bladder cancer ... See more keywords
Overview of Current and Future Adjuvant Therapy for Muscle-Invasive Urothelial Carcinoma
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DOI: 10.1007/s11864-018-0551-z
Abstract: Opinion statementMuscle-invasive bladder cancer (MIBC) has high metastatic potential at diagnosis but is still often curable with aggressive management, which may give patients the best odds for a favorable clinical outcome. The standard-of-care management of… read more here.
Keywords: chemotherapy; adjuvant therapy; cisplatin; cisplatin based ... See more keywords
Maloplatin-B, a Cisplatin-Based BODIPY-Tagged Mito-Specific "Chemo-PDT" Agent Active in Red Light.
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DOI: 10.1021/acs.inorgchem.1c00124
Abstract: Maloplatin-B, a cisplatin-based complex, namely [Pt(A-BOD)(NH3)2](NO3) (Pt-A-BOD) with a pendant boron-dipyrromethene (BODIPY) moiety, where HA-BOD is a methyl malonyl chloride derived monostyryl BODIPY ligand, was designed and developed as near-IR light (600-720 nm) organelle-targeting photodynamic… read more here.
Keywords: light; cisplatin based; red light; maloplatin cisplatin ... See more keywords
Predictive role of galectin-1 and integrin α5β1 in cisplatin-based neoadjuvant chemotherapy of bulky squamous cervical cancer
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DOI: 10.1042/bsr20170958
Abstract: Although galectin-1 and integrin α5β1 confer chemoresistance to certain types of cancer, whether their expression predicts the response to cisplatin-based neoadjuvant chemotherapy (NACT) in squamous cervical cancer remains unclear. Paired tumor samples (pre- and post-chemotherapy)… read more here.
Keywords: cisplatin based; cervical cancer; squamous cervical; galectin integrin ... See more keywords
Weekly versus triweekly cisplatin-based concurrent chemoradiotherapy in the treatment of locally advanced cervical carcinoma
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DOI: 10.1097/md.0000000000018663
Abstract: Supplemental Digital Content is available in the text read more here.
Keywords: triweekly cisplatin; based concurrent; concurrent chemoradiotherapy; cisplatin based ... See more keywords
Therapeutic effect of low frequency electric pulse therapy on cisplatin-based chemotherapy-induced nausea and vomiting in patients with lung adenocarcinoma: A prospective controlled study
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DOI: 10.1097/md.0000000000030088
Abstract: To explore the efficacy of low-frequency electric pulse therapy (LFEPT) combined with 2 antiemetics in the prevention and treatment of cisplatin-based chemotherapy-induced nausea and vomiting (CINV) in patients with lung adenocarcinoma. A total of 82… read more here.
Keywords: lung adenocarcinoma; group; cisplatin based; nausea vomiting ... See more keywords
Olanzapine 5 mg for Nausea and Vomiting in Patients with Nasopharyngeal Carcinoma Receiving Cisplatin-Based Concurrent Chemoradiotherapy
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DOI: 10.1155/2022/9984738
Abstract: Purpose To explore the efficacy and safety of adding olanzapine (5 mg or 10 mg) to 5-hydroxytryptamine type 3 receptor antagonists (5-HT3 RA), neurokinin-1 receptor antagonists (NK1 RA), and dexamethasone for nausea and vomiting in patients with… read more here.
Keywords: nausea; olanzapine; cisplatin based; based concurrent ... See more keywords
A Randomized Phase 2 Study of 5-Aminolevulinic Acid Hydrochloride and Sodium Ferrous Citrate for the Prevention of Nephrotoxicity Induced by Cisplatin-Based Chemotherapy of Lung Cancer
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DOI: 10.1159/000526977
Abstract: Introduction: Cisplatin-based chemotherapy was established in the 1980s, and it has been improved by the development of a short hydration protocol in lung cancer therapy. However, cisplatin-based chemotherapy is still associated with renal toxicity. Because… read more here.
Keywords: lung cancer; cisplatin based; group; based chemotherapy ... See more keywords
Role of immunotherapy in localized muscle invasive urothelial cancer
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DOI: 10.1177/17588359211045858
Abstract: The standard treatment for non-metastatic muscle-invasive bladder cancer (MIBC) is cisplatin-based neoadjuvant chemotherapy followed by radical cystectomy or trimodality therapy with chemoradiation in select patients. Pathologic complete response (pCR) to neoadjuvant chemotherapy is a reliable… read more here.
Keywords: chemotherapy; ici; cisplatin based; muscle invasive ... See more keywords